Abstract:Background: The recent discovery of a monoclonal antibody specific for TCR-Cb-1 (encoded by TCRCB1) heralded a new method for ab-T-cell clonality assessment by flow cytometry. Each ab-T-cell contains a b-chain constant region encoded by either TCRCB1 or TCRCB2. 1 Methods: Since 25 March 2021, following non-Hodgkin lymphoma immunophenotyping, selected specimens were further analysed with custom 5-colour panel tube(s) containing mouse monoclonal anti-TCR-Cb-1 (clone JOVI-1) conjugated to fluorescein isothiocyana… Show more
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