A Cruciform Petal-like (ZIF-8) with Bactericidal Activity against Foodborne Gram-Positive Bacteria for Antibacterial Food Packaging

Abstract

Most antibacterial nanomaterials used in food packaging act by releasing reactive oxygen species (ROS), which cannot efficiently have an inhibitory effect by penetrating the cell wall of Gram-positive Staphylococcus aureus. In this work, we used the cruciform petal-like zeolite imidazole framework-8 (ZIF-8) synthesized in the water phase which can release active Zn compounds in aqueous solution and exert a stronger inhibitory effect on S. aureus. The experimental results demonstrated that the aqueous cruciform petal-like ZIF-8 has the same photocatalytic activity as traditional ZIF-8 and can be applied in photocatalytic bacterial inactivation. The cruciform petal-like ZIF-8 was also shown to release active Zn compounds in aqueous solution with a better antibacterial effect against S. aureus, reaching 95% inactivation efficiency. The antibacterial effect was therefore 70% higher than that of traditional ZIF-8. Based on its excellent antibacterial properties, we loaded petal-like ZIF-8, PDA and PVA onto ordinary fibers to prepare ZIF-8-Film. The results further showed that ZIF-8-Film has a high filtration capacity, which can be used in antibacterial packaging material with the required air permeability. Moreover, ZIF-8-Flim can clean the surface on its own and can maintain a sterile environment. It is different from other disposable materials on the market in that it can be reused and has a self-disinfection function.

Biodegradable Microneedle Array-Mediated Transdermal Delivery of Dimethyloxalylglycine-Functionalized Zeolitic Imidazolate Framework-8 Nanoparticles for Bacteria-Infected Wound Treatment

“…After 30 min coincubation in PBS, we found that the fluorescence intensity of DCFH dispersions was positively correlated to the concentration of the ZIF-8 suspension (Figure 2F), indicating that a higher concentration of ZIF-8 NPs tended to generate a higher concentration of ROS to kill bacteria more efficiently. 47 As the schematic diagram (Figure 2G) showed, the antibacterial mechanisms of Zn-ZIF-8 NPs may include induced ROS generation that leads to oxidative stress 9,47 and disrupted expression of intracellular nucleic acid, 48 electrostatic interaction between positively charged ZIF-8 NPs and negatively charged bacterial cells, 45,46 and damage to some liposomes by the release of imidazole rings. 49 Biocompatibility of ZIF-8 and DMOG@ZIF-8 In Vitro.…”

Dual-Enzyme Cascade Composed of Chitosan Coated FeS2 Nanozyme and Glucose Oxidase for Sensitive Glucose Detection

“…The good shelf life of the FeS 2 /CS@Gox system will also further improve its application in the detection of real samples. The nanozyme-based glucose-sensing system offers a good detection limit [ 43 ], and our system offers obvious benefits over other systems ( Table 1 ). In conclusion, the FeS 2 /CS@Gox system constructed by the immobilized enzyme strategy has excellent sensitivity, selectivity, and shelf life and is a potential product for glucose detection.…”

Chitosan Based Biodegradable Composite for Antibacterial Food Packaging Application

“…Recently, several approaches have been adopted to modify chitosan to achieve the desired food-packaging qualities. Incorporating different additives such as essential oils and plant extracts with chitosan significantly enhances the antibacterial and antioxidant properties, the current trend in a coating that improves the shelf life [ 11 , 12 , 13 , 14 ]. Additional modifications with starch, alginate, and pectin improve mechanical properties [ 15 ].…”