A cross‐sectional cohort study on the skin microbiota in patients with different acne durations

Sun, Lang; Wang, Qingqun; Wang, Huan; Huang, Jing; Yu, Zheng

doi:10.1111/exd.14951

Cited by 3 publications

(2 citation statements)

References 55 publications

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“…Additionally, polycyclic aromatic hydrocarbons (PAHs) have the potential to bring about detrimental alterations in the composition and functionality of the skin microbiota [13,14]. This could be associated with acne, as demonstrated by a study on the skin microbiota in individuals with acne, which revealed significant changes in the composition of the skin microbial community throughout the course of the disease [15].…”

Section: Description Of the State Of Knowledgementioning

confidence: 99%

Exploring the role of anthropogenic air pollutants in the pathogenesis of acne

Kubicka - Figiel,

Martyka,

Taborska

2024

Med Srod.

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Introduction and Objective.Increasing global urbanization has led to significant atmospheric air pollution. Airborne pollutants, including PM, O3, CO, NOx, and SO2, exert detrimental effects on the entire body, contributing to various skin diseases. The aim of this study was to review the literature on the effects of selected air pollutants on the development or exacerbation of acne vulgaris, and to elucidate the mechanisms responsible. Brief description of the state of knowledge. Existing studies offer insights into the substantial impact of anthropogenic air pollution on the onset and aggravation of acne. Pollution particles affect the skin on various levels, compromising the protective sebum layer, triggering oxidative stress and inflammatory responses, and instigating noteworthy alterations in skin cell structures. Summary. Reduction in the prevailing levels of anthropogenic air pollutants is crucial for curbing the incidence of acne and enhancing public health. This skin condition detrimentally impacts the quality of life and the mental well-being of those affected, particularly in an era that champions an idealized appearance. The incorporation of substances with antioxidant and anti-inflammatory properties, fortifying the skin barrier, could also prove beneficial. Further research is imperative to deepen our understanding of the relationship between air pollution and acne, as well as to explore effective strategies for shielding the skin from pollution.

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Section: Description Of the State Of Knowledgementioning

confidence: 99%

Exploring the role of anthropogenic air pollutants in the pathogenesis of acne

Kubicka - Figiel,

Martyka,

Taborska

2024

Med Srod.

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“…The clinical manifestations encompass a diverse range of acneiform lesions, including comedones, papules, pustules, nodules, and cysts. These are often accompanied by excessive sebum secretion (1)(2)(3). Acne, affecting 9.4% of the global population, ranks as the eighth most prevalent disease worldwide.…”

Section: Introductionmentioning

confidence: 99%

Research progress on the role of macrophages in acne and regulation by natural plant products

Zhao,

Wang,

et al. 2024

Front. Immunol.

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Acne vulgaris is one of the most common skin diseases. The current understanding of acne primarily revolves around inflammatory responses, sebum metabolism disorders, aberrant hormone and receptor expression, colonization by Cutibacterium acnes, and abnormal keratinization of follicular sebaceous glands. Although the precise mechanism of action remains incompletely understood, it is plausible that macrophages exert an influence on these pathological features. Macrophages, as a constituent of the human innate immune system, typically manifest distinct phenotypes across various diseases. It has been observed that the polarization of macrophages toward the M1 phenotype plays a pivotal role in the pathogenesis of acne. In recent years, extensive research on acne has revealed an increasing number of natural remedies exhibiting therapeutic efficacy through the modulation of macrophage polarization. This review investigates the role of cutaneous macrophages, elucidates their potential significance in the pathogenesis of acne, a prevalent chronic inflammatory skin disorder, and explores the therapeutic mechanisms of natural plant products targeting macrophages. Despite these insights, the precise role of macrophages in the pathogenesis of acne remains poorly elucidated. Subsequent investigations in this domain will further illuminate the pathogenesis of acne and potentially offer guidance for identifying novel therapeutic targets for this condition.

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