A critical review on the occurrence of resistomes in the environment and their removal from wastewater using apposite treatment technologies: Limitations, successes and future improvement

Anthony, Eric Tobechukwu; Ojemaye, Mike O.; Okoh, Omobola O.; Okoh, Anthony I.

doi:10.1016/j.envpol.2019.113791

Cited by 47 publications

(27 citation statements)

References 192 publications

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“…The results showed that the recoveries of AMP and KAM in hospital wastewater (≤95.65%) and chicken farm wastewater (≤96.51%) were lower than those in other water (≥99.53%). It could be deduced that the transport of antibiotics in aquaculture water and tap water is an effective method for removing the antibiotic contaminants because antibiotics would be adsorbed, hydrolyzed, photolyzed, and biodegraded, among others, during their transport [33,34]. Furthermore, the high recovery and low RSD % indicated that the established method possesses a great selectivity and anti-interference capability, which could detect AMP and KAM in environmental water.…”

Section: Real Sample Analysismentioning

confidence: 99%

Simultaneous Quantification of Ampicillin and Kanamycin in Water Samples Based on Lateral Flow Aptasensor Strip with an Internal Line

et al. 2021

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In this work, a simple and rapid method based on the lateral flow assay (LFA) has been developed for the detection of dual antibiotics. To achieve the quantitative assay and to reduce the non-specific adsorption, an internal system has been developed. A non-specific DNA was exploited as an internal standard and could be recognized by the DNA marker that was coated at the internal line. Two different kinds of aptamers were applied to recognize ampicillin (AMP) and kanamycin (KAM), and the distance between the detection line and conjugate pad was then optimized. Under the optimum conditions, the quantitative assays of AMP (R2 = 0.984) and KAM (R2 = 0.990) were achieved with dynamic ranges of 0.50 to 500.0 ng/L, and of 0.50 to 1000.0 ng/L, respectively. The LOQs of AMP and KAM were 0.06 ng/L and 0.015 ng/L, respectively. Finally, the proposed method has been successfully applied to analyze aquaculture water, tap water, and lake water, and hospital wastewater, indicating the established method could be used to monitor the environment.

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Section: Real Sample Analysismentioning

confidence: 99%

Simultaneous Quantification of Ampicillin and Kanamycin in Water Samples Based on Lateral Flow Aptasensor Strip with an Internal Line

et al. 2021

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“…This issue becomes particularly serious when pathogenic bacteria carrying antibiotic-resistant genes (ARG) re-grow after disinfection treatments are applied to WWTP effluents. In the recent years, due to the high consumption of antibiotics, ARB and ARG have been increasingly found and monitored in waters of different origins such as municipal and hospital WW, surface water and groundwater, sediments, water used in agriculture, drinking water, and even in the air, crops, and soils [43,63]. Various disinfection methods based on sunlight or artificial sunlight, such as UV/solar/H 2 O 2 , Fenton and photo-Fenton, and heterogeneous catalysis with TiO 2 , have been tested for treating numerous ARG and ARB [27]; however, although the majority of AOPs have yielded very high levels of inactivation, further investigation is still needed to find solutions to secondary contamination, for example, the release and transfer of ARG among microbial cells, photo-reactivation, etc.…”

Section: Abstract' Trends and Progressmentioning

confidence: 99%

“…Various disinfection methods based on sunlight or artificial sunlight, such as UV/solar/H 2 O 2 , Fenton and photo-Fenton, and heterogeneous catalysis with TiO 2 , have been tested for treating numerous ARG and ARB [27]; however, although the majority of AOPs have yielded very high levels of inactivation, further investigation is still needed to find solutions to secondary contamination, for example, the release and transfer of ARG among microbial cells, photo-reactivation, etc. [63], which imply the use of post-treatments following AOP [64].…”

Section: Abstract' Trends and Progressmentioning

confidence: 99%

Worldwide Research Trends on Solar-Driven Water Disinfection

Martín

Brindley

Pérez

et al. 2021

IJERPH

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“Ensure access to water for all”, states Goal 6 of the UN’s Sustainable Development Goals. This worldwide challenge requires identifying the best water disinfection method for each scenario. Traditional methods have limitations, which include low effectiveness towards certain pathogens and the formation of disinfection byproducts. Solar-driven methods, such as solar water disinfection (SODIS) or solar photocatalysis, are novel, effective, and financially and environmentally sustainable alternatives. We have conducted a critical study of publications in the field of water disinfection using solar energy and, hereby, present the first bibliometric analysis of scientific literature from Elsevier’s Scopus database within the last 20 years. Results show that in this area of growing interest USA, Spain, and China are the most productive countries in terms of publishing, yet Europe hosts the most highly recognized research groups, i.e., Spain, Switzerland, Ireland, and UK. We have also reviewed the journals in which researchers mostly publish and, using a systematic approach to determine the actual research trends and gaps, we have analyzed the capacity of these publications to answer key research questions, pinpointing six clusters of keywords in relation to the main research challenges, open areas, and new applications that lie ahead. Most publications focused on SODIS and photocatalytic nanomaterials, while a limited number focused on ensuring adequate water disinfection levels, testing regulated microbial indicators and emerging pathogens, and real-world applications, which include complex matrices, large scale processes, and exhaustive cost evaluation.

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“…Carrizzo et al [168] described the fractionation of Spirulina lysates by a treatment that simulates gastrointestinal digestion (GID). From these extracts, four peptides were obtained and characterized by mass spectrometry (SP (3)(4)(5)(6)). In a further step, these peptides were synthesized by Fmoc chemistry and tested for vasorelaxation in an ex vivo model consisting of mouse mesenteric arteria.…”

Section: Antihypertensive Activitymentioning

confidence: 99%

“…The overuse, and often misuse, of antimicrobials in clinics [3], is one of the main reasons of AMR, but not the only one. The induction of antibiotic resistance outside nosocomial settings, strongly associated to the antibiotic use in livestock farming [4], aquaculture [5], and the uncontrolled dumping of antibiotics into the environment [6,7], account for the horizontal transmission of antibiotic-resistance traits out of the nosocomial setting. Furthermore, zoonosis may act as a reservoir for resistant organisms.…”

Section: Introductionmentioning

confidence: 99%

Cyanobacteria and Eukaryotic Microalgae as Emerging Sources of Antibacterial Peptides

et al. 2020

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Cyanobacteria and microalgae are oxygen-producing photosynthetic unicellular organisms encompassing a great diversity of species, which are able to grow under all types of extreme environments and exposed to a wide variety of predators and microbial pathogens. The antibacterial compounds described for these organisms include alkaloids, fatty acids, indoles, macrolides, peptides, phenols, pigments and terpenes, among others. This review presents an overview of antibacterial peptides isolated from cyanobacteria and microalgae, as well as their synergism and mechanisms of action described so far. Antibacterial cyanopeptides belong to different orders, but mainly from Oscillatoriales and Nostocales. Cyanopeptides have different structures but are mainly cyclic peptides. This vast peptide repertoire includes ribosomal and abundant non-ribosomal peptides, evaluated by standard conventional methodologies against pathogenic Gram-negative and Gram-positive bacteria. The antibacterial activity described for microalgal peptides is considerably scarcer, and limited to protein hydrolysates from two Chlorella species, and few peptides from Tetraselmis suecica. Despite the promising applications of antibacterial peptides and the importance of searching for new natural sources of antibiotics, limitations still persist for their pharmaceutical applications.

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A critical review on the occurrence of resistomes in the environment and their removal from wastewater using apposite treatment technologies: Limitations, successes and future improvement

Cited by 47 publications

References 192 publications

Simultaneous Quantification of Ampicillin and Kanamycin in Water Samples Based on Lateral Flow Aptasensor Strip with an Internal Line

Simultaneous Quantification of Ampicillin and Kanamycin in Water Samples Based on Lateral Flow Aptasensor Strip with an Internal Line

Worldwide Research Trends on Solar-Driven Water Disinfection

Cyanobacteria and Eukaryotic Microalgae as Emerging Sources of Antibacterial Peptides

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