A critical review of the mechanisms involved in the occurrence of growth-related abnormalities affecting broiler chicken breast muscles

Soglia, Francesca; Petracci, Massimiliano; Davoli, Roberta; Zappaterra, Martina

doi:10.1016/j.psj.2021.101180

Cited by 57 publications

(64 citation statements)

References 126 publications

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“…The rapid growth and inadequate vascularization in breast induced the hypoxic conditions, then kinds of response mechanisms such as energetic metabolism, inflammation, degeneration, and regeneration were modified or triggered. All these alterations were strictly related to the progression of myopathic disorders ( Soglia et al, 2021 ). In addition, significant accumulation of lipofuscin was associated with the development of WB ( Hasegawa et al, 2021 ).…”

Section: Discussionmentioning

confidence: 99%

Serum Creatine Kinase as a Biomarker to Predict Wooden Breast in vivo for Chicken Breeding

Kong

Zhao

et al. 2021

Front. Physiol.

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The present study aimed to find a blood marker for the prediction of wooden breast (WB) in live broiler to assist the genetic selection of fast-growing chickens. The experiments were carried out with two chicken flocks: 250 male broilers in flock 1 and 100 male and female broilers in flock 2. Both flocks were slaughtered and measured. The breast filets were assessed by combining subjective scoring and compression force at 28 (flock 1 only) and 42 days of age. The enzyme activity in serum and breast tissue (flock 1 only) of normal and affected groups was tested. The results showed that the compression force was significantly different between the normal and affected groups at 28 and 42 days of age (P < 0.001), and it increased significantly with rising WB and WS scores. The serum creatine kinase (CK) value increased significantly with rising compression force at 42 days of age (P < 0.001). The serum CK positively correlated with compression force (r = 0.608; P < 0.001) and the linear regression equation (serum CK = 0.9960∗compression force + 1.884) was established for the line studied. The association between serum CK and compression force is consistent between flocks 1 and 2. In conclusion, our study confirmed that compression force could be the quantitative indicator to differentiate breast filets and found that serum CK could be a candidate biomarker to predict WB in live broilers and assist genetic selection in broiler breeding.

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Section: Discussionmentioning

confidence: 99%

Serum Creatine Kinase as a Biomarker to Predict Wooden Breast in vivo for Chicken Breeding

Kong

Zhao

et al. 2021

Front. Physiol.

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“…However, to the best of our knowledge, any published study specifically speculates about those divergences. Nevertheless, intensive selection practices carried out over years permitted to accomplish a remarkable development of the breast muscle, so much so that the impressive thickness of its cranial section might compress the pectoral artery, reducing muscular oxygenation (Soglia et al, 2021). Thus, a feasible hypothesis for the abovementioned intra-fillet variations may rely on a different blood flow between the surface of the muscle, phenotypically exhibiting the defect, and its deep counterpart.…”

Section: Implications On Meat Quality and Practical Solutionsmentioning

confidence: 99%

“…Considering the recentness of SM condition, the mechanisms underpinning its appearance are still partially unknown and less investigated compared to WB and WS. However, the same histological alterations shared among WB, WS, and SM fillets suggest a common network of causative mechanisms responsible for their occurrence, in which cellular stress and hypoxiacaused by muscle hypertrophy induced by selection -play a key role (Sihvo et al, 2018;Young and Rasmussen, 2020;Soglia et al, 2021). Considering their common histological traits, one of the most compelling challenges for the scientific community is to determine the reason why growth-related myopathies phenotypically manifest differently.…”

Section: Current Challenges and Potential Future Developmentsmentioning

confidence: 99%

Spaghetti Meat Abnormality in Broilers: Current Understanding and Future Research Directions

2021

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Spaghetti meat (SM) is a recent muscular abnormality that affects the Pectoralis major muscle of fast-growing broilers. As the appellative suggests, this condition phenotypically manifests as a loss of integrity of the breast muscle, which appears soft, mushy, and sparsely tight, resembling spaghetti pasta. The incidence of SM can reach up to 20% and its occurrence exerts detrimental effects on meat composition, nutritional value, and technological properties, accounting for an overall decreased meat value and important economic losses related to the necessity to downgrade affected meats. However, due to its recentness, the causative mechanisms are still partially unknown and less investigated compared to other muscular abnormalities (i.e., White Striping and Wooden Breast), for which cellular stress and hypoxia caused by muscle hypertrophy are believed to be the main triggering factors. Within this scenario, the present review aims at providing a clear and concise summary of the available knowledge concerning SM abnormality and concurrently presenting the existing research gaps, as well as the potential future developments in the field.

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“…Despite the studies searching for the causes of the WS development, efforts are still needed to understand and, consequently, reduce this problem. In a recent review by Soglia et al (2021) , the importance of gene expression studies to unravel the molecular mechanisms underlying the findings obtained by different techniques and approaches to understand myopathic disorders in a global manner was highlighted. Thus, gene expression studies evaluating normal and WS-affected tissues would provide additional support to find the triggering pathways of this myopathy.…”

Section: Introductionmentioning

confidence: 99%

Differential Expression of Myogenic and Calcium Signaling-Related Genes in Broilers Affected With White Striping

et al. 2021

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White Striping (WS) has been one of the main issues in poultry production in the last years since it affects meat quality. Studies have been conducted to understand WS and other myopathies in chickens, and some biological pathways have been associated to the prevalence of these conditions, such as extracellular calcium level, oxidative stress, localized hypoxia, possible fiber-type switching, and cellular repairing. Therefore, to understand the genetic mechanisms involved in WS, 15 functional candidate genes were chosen to be analyzed by quantitative PCR (qPCR) in breast muscle of normal and WS-affected chickens. To this, the pectoral major muscle (PMM) of 16 normal and 16 WS-affected broilers were collected at 42 days of age and submitted to qRT-PCR analysis. Out of the 15 genes studied, six were differentially expressed between groups. The CA2, CSRP3, and PLIN1 were upregulated, while CALM2, DNASE1L3, and MYLK2 genes were downregulated in the WS-affected when compared to the normal broilers. These findings highlight that the disruption on muscle and calcium signaling pathways can possibly be triggering WS in chickens. Improving our understanding on the genetic basis involved with this myopathy might contribute for reducing WS in poultry production.

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A critical review of the mechanisms involved in the occurrence of growth-related abnormalities affecting broiler chicken breast muscles

Cited by 57 publications

References 126 publications

Serum Creatine Kinase as a Biomarker to Predict Wooden Breast in vivo for Chicken Breeding

Serum Creatine Kinase as a Biomarker to Predict Wooden Breast in vivo for Chicken Breeding

Spaghetti Meat Abnormality in Broilers: Current Understanding and Future Research Directions

Differential Expression of Myogenic and Calcium Signaling-Related Genes in Broilers Affected With White Striping

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