Abstract:BackgroundA new derived (i.e., calculated) endpoint of developmental toxicology has appeared in a very few studies since 1990. This endpoint is adjusted mean live fetal weight per litter or adjusted fetal weight. Given our lack of familiarity with the endpoint, we evaluated the basis, prevalence, methods, and usefulness in embryo‐fetal developmental toxicity (EFDT) studies in rats.MethodsLiterature searches were performed with key terms using PubMed and Google Scholar. Major textbooks were consulted but lack o… Show more
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