A convenient synthesis of the tricyclo[3,2,1,02,7]octane system: a simplified synthesis of the diterpenoid trachylobane

Abstract

A convenient and efficient method for the THE tricyclo[3,2,1,02~7]octane system is a novel structural construction of the tricyclo[3,2,l,0~~7]octane system, feature of a group of sesquiterpenoids related to the naturinvolving a homoallylic cyclization, is reported ; the ally occurring hydrocarbon ishwarane (1)l and of a larger application of this method results in a considerably group of diterpenoids of which the naturally occurring simplified and more efficient synthesis of trachylobane. parent hydrocarbon is trachylobane (11) . % We have