A Convenient Synthesis of Alkyl- and Dialkylphenanthren-9-ylamines

Abstract

A variety of alkyl-and dialkylphenanthren-9-ylamines 1 and 2 have been prepared by radical-mediated cyclizations of the corresponding diaryleneamines 3 issued from Horner reactions between appropriate phosphorylated dibenzylamines 4 and halogenoarylaldehydes 5.

Horner−Wadsworth−Emmons Reagents as Azomethine Ylide Analogues: Pyrrole Synthesis via (3 + 2) Cycloaddition

“…Amido-substituted phosphonates can be generated by the reaction of in situ formed α-chloroamides with phosphites . For example, the reaction of p -tolyl(H)CNBn and anisoyl chloride in acetonitrile leads to the formation of α-chloroamide 8 within minutes at ambient temparature (Scheme ).…”