“…In C. maenas, [ 3 H]5-diketol is ultimately converted to 3DE and 25dE by C. maenas YO cells [36]. [ 3 H]5-ketodiol is hydroxylated at C2, C22, or C25 in C. maenas YOs to produce 22,25-deoxyecdysone (22,25dE), 2,25-deoxyecdysone (2,25dE), or 2,22-dideoxyecdysone (2,22dE), respectively [40][41][42]. 2,22dE and 2,25dE are converted to ecdysone and 25dE, respectively, and secreted by the YO [40,41].…”