A Convenient Route to Diverse Heterocycles through an Addition of β-Amino Carbonyl Compounds to 3-Halogeno-4-methoxybenzynes

Abstract

[reaction: see text] 3-Halogeno-4-methoxybenzynes 5 generated from 5-(3-halogeno-4-methoxyphenyl)thianthrenium perchlorates 1 and LDA in THF at reflux reacted with various beta-amino carbonyl compounds and 2-aminophenyl benzenesulfonate etc. to give diverse heterocyclic compounds.

Auto‐Tandem Catalysis: Synthesis of Acridines by Pd‐Catalyzed C=C Bond Formation and C(sp2)–N Cross‐Coupling

“…The Larock group developed an acridine synthesis via aryne intermediates (Scheme , c) 7d. A similar protocol was reported by Kim, using a different benzyne precursor 7e…”

Addition of thianthrene cation radical to non-conjugated dienes—Part I: Addition to one double bond

“…Numerous reactions of the thianthrene cation radical with nucleophiles, electron-rich aromatics, alcohols, azoalkanes, organometallics, ketones, and various derivatives of aldehydes and ketones are to be found, and have been in part reviewed, in the literature [1][2][3][4][5][6][7][8][9][10][11][12][13][14]. Among these reactions, additions to alkenes and cycloalkenes, which were first discovered more than 20 years ago [15,16], have drawn, recently, further extensive interest [17][18][19][20].…”

Interaction of Organonitriles with Electron Rich Calix[4]arene Derivatives on Gold Substrates

“…The synthesis of 1, 2, and 3 has been reported elsewhere [6][7][8]. The calix [4]arene derivatives were dissolved in chloroform to generate self-assembled monolayer on gold substrates.…”