A convenient and efficient synthesis of 3-benzofuryl-substituted phthalides
Yongjun Zang,
Qilin Xu,
Guosi Li
et al.
Abstract:A highly efficient and convenient procedure for straightforward synthesizing structurally diverse 3-benzofurylsubstituted phthalides is developed with moderate to excellent yields via cyclization reactions of benzofurans with 2-carbonyl-benzoic acid. The reaction features readily available starting materials, a broad scope, and a high atom economy. Besides, an interesting regioselective was observed in some cases.
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