A controlled trial of verapamil in patients after acute myocardial infarction: Results of the calcium antagonist reinfarction italian study (CRIS)

2014 AHA/ACC Guideline for the Management of Patients With Non–ST-Elevation Acute Coronary Syndromes

“…The ACI-TIPI (Acute Cardiac Ischemia Time-Insensitive Predictive Instrument) project found that older age, male sex, chest or left arm pain, and chest pain or pressure were the most important findings, and each increased the likelihood of ACS. 111,112 The relief of chest pain with nitroglycerin is not predictive of ACS. One study reported that sublingual nitroglycerin relieved symptoms in 35% of patients with documented ACS compared with 41% of patients without ACS.…”

Effects of Medication on Cardiovascular Events in the Japanese Coronary Artery Disease (JCAD) Study

“…18,19 In this study, short-acting CCBs were rarely used (data not shown), and future investigation may be required to elucidate the deleterious result obtained in this study.…”

Guideline for the management of patients with acute coronary syndromes without persistent ECG ST segment elevation

“… Evidence level Ib 8.5 Medical treatment for prognostic benefit: A meta-analysis of four studies of 4700 patients with unstable angina demonstrated a 13% reduction in the risk of developing myocardial infarction among patients treated with β blockers 91. There is some evidence that diltiazem is associated with a reduction in reinfarction, not mortality, after non-Q wave myocardial infarction, but only in those patients with preserved left ventricular function92-94; similar findings have been reported with verapamil 95. In subgroup analysis of another study, verapamil given after myocardial infarction to those patients without heart failure was associated with a lower mortality 96.…”