Objective: To analyze the feasibility of different surgical methods for treating uterine fibroids and their impact on ovarian function. Methods: 90 patients with uterine fibroids admitted to our hospital from December 2018 to April 2023 were divided into Group A and Group B, with 45 patients in each group. Group A underwent laparoscopic myomectomy (LM) and Group B underwent transcervical resection of myoma (TCRM). The patients were followed up 3 months after surgery and their clinical indexes were compared. Results: The duration of hospitalization, surgery, anal ventilation, and getting out of bed were shorter in Group B. Besides, Group B also experience less intraoperative bleeding (P < 0.05). There was no difference in the follicle-stimulating hormone (FSH), luteinizing hormone LH, estradiol (E2), and anta follicle count (AFC) levels between the two groups after surgery (P > 0.05). The Female Sexual Function Index scores of two groups increased significantly after surgery, with Group B showing a more drastic increase (P < 0.05); The VAS ratings of the two groups showed a decreasing trend 1–5 days after surgery, with Group B showing a larger decrease (P < 0.05). There was no difference in the incidence of complications between the two groups within 3 months after surgery (P > 0.05). Conclusion: Both LM and TCRM are effective in treating uterine fibroids with little impact on ovarian function and complications. However, TCRM is associated with reduced bleeding, quicker postoperative recovery, decreased pain, and an enhanced quality of sexual life. Therefore, this surgical approach appears more beneficial for improving prognosis.