A consensus statement on the management of pregnancy and delivery in women who are carriers of or have bleeding disorders

Dunkley, Scott; Russell, Susan; Rowell, J.; Barnes, Chris; Baker, Ross; Sarson, Megan l; Street, Alison

doi:10.5694/j.1326-5377.2009.tb02887.x

Cited by 29 publications

(45 citation statements)

References 28 publications

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“…It is also preferable for women to know their carrier status before becoming pregnant so that they can make an informed decision about starting a family [54]. Guidelines for clinicians on the management of pregnancy and delivery, such as the consensus statement of the Australian Haemophilia Centre Directors’ Organisation [55], may indirectly provide useful evidence‐based advice to haemophilia carriers.…”

Section: Discussionmentioning

confidence: 99%

Psychosocial aspects of haemophilia: a systematic review of methodologies and findings

Cassis¹,

Querol²,

Forsyth³

et al. 2011

Haemophilia

103

155

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Psychosocial factors have a significant impact on quality of life for patients with chronic diseases such as haemophilia. Interventions to support the psychosocial needs of patients and their families, such as offering information and assistance, clarifying doubts, and teaching coping strategies to minimize the impact of disabilities, may help to maximize patient outcomes and improve quality of life for their families. The aim of this study was to evaluate the current literature on psychosocial aspects of haemophilia. Literature searches were performed using the PubMed database to identify studies evaluating psychosocial stressors in persons with haemophilia. Articles pertaining to the HIV epidemic were excluded from the analysis, as were those published before 1997. The literature reviews identified 24 studies, covering a range of different populations, generally with small cohorts (n < 100). Most studies were questionnaire based, with almost no overlap in terms of the instruments used. Only one study combined questionnaire techniques with qualitative methods. Except for two European studies, all publications reported data from a single country. Overall, studies tended to show that quality of life is reduced in persons with haemophilia, with a potential impact on education and employment, particularly when prophylactic treatment is not available. Carrier status in women may have a psychosocial impact and affect reproductive choices. Data on psychosocial aspects of the haemophilia life cycle are lacking in the published literature, along with data from developing countries. There is a need for more international, multifaceted research to explore and quantify the social and psychological aspects of life with haemophilia.

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Section: Discussionmentioning

confidence: 99%

Psychosocial aspects of haemophilia: a systematic review of methodologies and findings

Cassis¹,

Querol²,

Forsyth³

et al. 2011

Haemophilia

103

155

View full text Add to dashboard Cite

show abstract

“…In women with Glanzmann thrombasthenia or Bernard–Soulier syndrome, blood and platelet transfusion should be avoided wherever possible because of the risk of sensitisation to antigens not present on their own platelets (Box 1). No treatment is required antenatally, but the presence of anti‐human leukocyte antigen and anti‐platelet antibodies should be assessed before delivery.…”

Section: Management Of Pregnancy and Deliverymentioning

confidence: 99%

“…This statement is an update of the 2009 Australian Haemophilia Centre Directors’ Organisation (AHCDO) consensus statement on pregnancy and delivery management in women with inherited bleeding disorders . Over the past 9 years there have been key advances in the understanding and management of inherited bleeding disorders in pregnancy.…”

mentioning

confidence: 99%

Updated Australian consensus statement on management of inherited bleeding disorders in pregnancy

Dunkley

Curtin

Marren

et al. 2019

Medical Journal of Australia

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IntroductionThere have been significant advances in the understanding of the management of inherited bleeding disorders in pregnancy since the last Australian Haemophilia Centre Directors’ Organisation (AHCDO) consensus statement was published in 2009. This updated consensus statement provides practical information for clinicians managing pregnant women who have, or carry a gene for, inherited bleeding disorders, and their potentially affected infants. It represents the consensus opinion of all AHCDO members; where evidence was lacking, recommendations have been based on clinical experience and consensus opinion.Main recommendationsDuring pregnancy and delivery, women with inherited bleeding disorders may be exposed to haemostatic challenges. Women with inherited bleeding disorders, and their potentially affected infants, need specialised care during pregnancy, delivery, and postpartum, and should be managed by a multidisciplinary team that includes at a minimum an obstetrician, anaesthetist, paediatrician or neonatologist, and haematologist. Recommendations on management of pregnancy, labour, delivery, obstetric anaesthesia and postpartum care, including reducing and treating postpartum haemorrhage, are included. The management of infants known to have or be at risk of an inherited bleeding disorder is also covered.Changes in management as a result of this statementKey changes in this update include the addition of a summary of the expected physiological changes in coagulation factors and phenotypic severity of bleeding disorders in pregnancy; a flow chart for the recommended clinical management during pregnancy and delivery; guidance for the use of regional anaesthetic; and prophylactic treatment recommendations including concomitant tranexamic acid.

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“…35 Administration of vitamin K withheld until bleeding status determined. Abnormal results should be confirmed with peripheral blood sample and infant referred to haemophilia treatment centre or haematologist.…”

Section: Testing Of the Newbornmentioning

confidence: 99%

Women with bleeding disorders: Clinical and psychological issues

McLintock

2018

Haemophilia

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A consensus statement on the management of pregnancy and delivery in women who are carriers of or have bleeding disorders

Cited by 29 publications

References 28 publications

Psychosocial aspects of haemophilia: a systematic review of methodologies and findings

Psychosocial aspects of haemophilia: a systematic review of methodologies and findings

Updated Australian consensus statement on management of inherited bleeding disorders in pregnancy

Women with bleeding disorders: Clinical and psychological issues

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