A conjunctival leiomyoma

Brannan, S; Cheung, D.; Trotter, Simon; Tyler, Alan J.; Reuser, Tristan

doi:10.1016/s0002-9394(03)00399-4

Cited by 5 publications

(7 citation statements)

References 3 publications

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“…A MEDLINE search using keywords “Conjuctival Leiomyoma” revealed just one reported case by Brannan et al in 2003. [3] The second case report by Ghayoor et al[2] was published in a regional journal. This case adds to the total number of cases of conjuctival leiomyoma reported in the literature to date.…”

Section: Discussionmentioning

confidence: 99%

“…[6] Ciliary body is known to be affected by leiomyoma. [3] Leiomyoma has a propensity to affect the peripheral choroid rather than the posterior choroid. [7] Heegaard and Prause reported a case of caruncle leiomyoma in 1998.…”

Section: Discussionmentioning

confidence: 99%

“…However, it has been reported in literature that leiomyomas arising from the supraciliary space can spare the underlying uveal tract and erode the sclera. [3]…”

Section: Discussionmentioning

confidence: 99%

“…The histology of the mentioned lesions is usually characteristic. [3] Immuno-histochemistry, in some cases, can be a useful diagnostic aid. The conjunctival leiomyoma in this case stained strongly with smooth muscle markers (anti-smooth muscle actin antibody) [Figure 4].…”

Section: Discussionmentioning

confidence: 99%

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Conjunctival leiomyoma; a rare tumor of the ocular surface

Afghani¹,

Khan²,

Mansoor³

2016

J Ophthalmic Vis Res

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Purpose:To report a case of conjuctival leiomyoma.Case Report:An 18-year-old female patient presented with a conjunctival growth in the left eye for a 2-year-period with no change in size. She merely presented for cosmetic reasons. Visual acuity was 20/20 in each eye. The lesion had prominent vessels and was not adherent to the sclera. The growth resembled a benign lesion of the conjunctiva. The tough and vascular tissue was excised and sent for histopathology. The defect was covered by an end to end conjunctival suturing. Histopathology showed the lesion to be conjunctival leiomyoma. Trichome was used to highlight the spindle shaped cells and immuno-histochemistry using anti-smooth muscle actin antibody and Vimentin was applied to confirm the diagnosis.Conclusion:This case adds to the total number of cases of conjuctival leiomyoma reported in the literature to date. An ophthalmologist needs to think beyond a common mass when encountering a conjunctival growth extending onto the cornea.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

“…However, it has been reported in literature that leiomyomas arising from the supraciliary space can spare the underlying uveal tract and erode the sclera. [3]…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Conjunctival leiomyoma; a rare tumor of the ocular surface

Afghani¹,

Khan²,

Mansoor³

2016

J Ophthalmic Vis Res

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“…In the human literature, there are multiple reports of ocular or periocular leiomyomas arising from the orbit, eyelid, conjunctiva, iris, ciliary body, and choroid . Ocular leiomyomas are considered rare as these case reports are very sporadic throughout the literature.…”

Section: Introductionmentioning

confidence: 99%

Leiomyoma of the third eyelid in a dog

Mathes

Noble

Ellis

2015

Veterinary Ophthalmology

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A 14-year-old neutered male Dachshund presented for the evaluation of oculus dexter (OD) third eyelid elevation ongoing for approximately 2 months. Complete ophthalmic examination revealed a large, nonpainful, well-demarcated, soft mass at the base of the right third eyelid causing elevation and mild hyperemia. The mass was freely moveable with the third eyelid, and no right globe deviation was noted. No other abnormalities were noted on physical examination, routine blood chemistry, complete blood count, serum T4, urinalysis, or urine cortisol/creatinine ratio. Ocular B-mode ultrasonography showed an anechoic, well-demarcated, homogenous, soft tissue mass at the base of the third eyelid with no orbital extension. A leiomyoma was diagnosed after multiple punch biopsies were obtained from the palpebral surface of the mass. The right third eyelid was excised surgically. Histopathology confirmed a completely excised, nodular, unencapsulated, expansile mass within the third eyelid. Positive smooth muscle actin and negative S-100 immunohistochemistry confirmed a leiomyoma. Bundles of normal smooth muscle were also present adjacent to the mass. The mass was compressing the adjacent lacrimal gland and associated with moderate dacryoadenitis. Twelve months postoperatively, the right globe position and motility remain normal with no evidence of mass regrowth. To the author's knowledge, this is the first reported case of a leiomyoma of the third eyelid in any species. In this case, the mass was completely excised and no regrowth has occurred twelve months after surgery. This case along with independently reviewed canine third eyelids clearly demonstrates the presence of smooth muscle within the canine third eyelid.

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Presentation of a Smooth Muscle Hamartoma in the Bulbar Conjunctiva of an Adolescent Boy: A Case Report and Review of Literature

Sayegh

Tang

Khzam

et al. 2023

Cornea

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Purpose:The aim of this study was to describe a novel presentation of conjunctival smooth muscle hamartoma and review the histopathologic findings of this entity.Methods:A 17-year-old African American adolescent boy presented with a pink, nontender lesion of the right bulbar conjunctiva that did not improve with medical management. He had no previous medical or ocular history. The lesion was excised.Results:Histopathologic examination disclosed morphologically benign smooth muscle bundles within the substantia propria that stained positively for smooth muscle actin, vimentin, and desmin consistent with the diagnosis of a smooth muscle hamartoma.Conclusions:Although congenital smooth muscle hamartomas of the conjunctiva have been rarely reported in the literature, this is the first described case of a smooth muscle hamartoma presenting in adolescence in the bulbar conjunctiva. This lesion should be considered in the differential diagnosis for adolescents with similar appearing lesions.

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A conjunctival leiomyoma

Cited by 5 publications

References 3 publications

Conjunctival leiomyoma; a rare tumor of the ocular surface

Conjunctival leiomyoma; a rare tumor of the ocular surface

Leiomyoma of the third eyelid in a dog

Presentation of a Smooth Muscle Hamartoma in the Bulbar Conjunctiva of an Adolescent Boy: A Case Report and Review of Literature

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