A congenital soft tissue Ewing sarcoma in a newborn patient

Abstract

Congenital Ewing sarcoma is extremely rare. Here we present a newborn baby born with a mass on the left shoulder. Immunohistochemical staining showed congenital Ewing sarcoma. Chemotherapy and then surgical operation were planned, however the patient died before initiation of chemotherapy on the 30th day of life.

Congenital Ewing Sarcoma Presenting as a Rapidly Growing Neck Mass in a Newborn

“…The incidences of translocation-related sarcomas peak in those between 30 and 50 years old,10 while ESFTs are most often seen in White males between 5 and 20 years of age, with a total annual incidence rate of only 3 per million 5. Infant diagnosis is rare, with one study showing only 2.6% of all EWS cases presenting before 3 years of age11; soft-tissue or extraskeletal EWS is also relatively rare, only representing 4% of all ESFTs 12. Thus, congenital soft-tissue EWS is exceedingly rare and has been described exclusively in case reports—as few as 19 times in the English-language literature 3,12–16.…”

“…5 Infant diagnosis is rare, with one study showing only 2.6% of all EWS cases presenting before 3 years of age 11 ; soft-tissue or extraskeletal EWS is also relatively rare, only representing 4% of all ESFTs. 12 Thus, congenital softtissue EWS is exceedingly rare and has been described exclusively in case reports-as few as 19 times in the English-language literature. 3,[12][13][14][15][16] Congenital softtissue EWS is rare; however, because of the aggressive nature and subsequent risk for airway compromise, neonatal nurses and physicians must consider malignancy on their differential when evaluating neonates with neck masses and involve appropriate levels of subspecialty care.…”

Mesenchymal tumour or amniotic band syndrome in a newborn – a diagnostic dilemma

“…najčešći su nefroblastomi i neuroblastomi, rjeđe mezenhimni tumori. 8,9 većinom se dijagnoza postavlja u djece starije od godinu dana, no iako sporadično, mezenhimni embrionalni solidni tumori opisani su i u novorođenčadi. 10,11 nema spoznaja o tome kakva je pojavnost mezenhimnih tumora u djece sa SaB-om.…”

Ewing Sarcoma Presenting as a Congenital Scalp Mass

“…Skeletal EWS is described as belonging to a collective group known as the “Ewing family of tumors” in which extraosseous Ewing sarcoma (EES) and primitive neuroendocrine tumors are also included. Extraosseous Ewing sarcoma differs from EWS in that it arises from the soft tissues, often presenting as an enlarging well-circumscribed mass that, given its characteristics, may be mistaken for a benign lesion (Akçalı et al, 2017). Congenital presentation of this tumor family is exceedingly rare, with our literature review revealing roughly 40 documented cases.…”