A concise protocol for the synthesis of 2-alkenylindoles through [4 + 1] annulation of aminobenzyl phosphonium salts with acrylaldehydes

Abstract

A [4+1] annulation protocol is developed for the synthesis of various 2-alkenylindole derivatives starting from aminobenzyl phosphonium salts and cinnamaldehydes. In this process, the reaction proceeds efficiently without the usage...