A conceptual model of alcohol use and adherence to antiretroviral therapy: systematic review and theoretical implications for mechanisms of action

Woolf‐King, Sarah E.; Sheinfil, Alan Z.; Ramos, Jeremy; Foley, Jacklyn D.; Moskal, Dezarie; Firkey, Madison; Kellen, David; Maisto, Stephen A.

doi:10.1080/17437199.2020.1806722

Cited by 13 publications

(17 citation statements)

References 117 publications

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“…Creating and implementing HIV-related initiatives that are both relevant and culturally appropriate and that reach the groups most affected by HIV can be challenging. Despite ART's great success as a prevention method against the development of AIDS or HIVrelated deaths, adherence to ART medication is often poor [4,[25][26][27][28][29][30][31]. Treatment adherence (i.e., taking medication as prescribed) is generally regarded by healthcare professionals as the most important factor in HIV treatment success: nonadherence can contribute to treatment failure and disease progression [4].…”

Section: Alcohol Use and Art Adherencementioning

confidence: 99%

“…Despite ART's great success as a prevention method against the development of AIDS or HIVrelated deaths, adherence to ART medication is often poor [4,[25][26][27][28][29][30][31]. Treatment adherence (i.e., taking medication as prescribed) is generally regarded by healthcare professionals as the most important factor in HIV treatment success: nonadherence can contribute to treatment failure and disease progression [4]. When taken consistently and correctly, ART reduces both the amount of HIV in the body and the onward transmission of HIV [4,32].…”

Section: Alcohol Use and Art Adherencementioning

confidence: 99%

“…Substance use is often associated with poor HIV-related outcomes and an increased risk of HIV transmission [33][34][35]. Substance use is prevalent among PLWH, cited as one of the correlates of ART nonadherence and associated with medication nonadherence in studies such as Woolf-King et al and Hendershot et al [4,25]. While much of the literature has focused on the association between injection drug use (IDU) and ART adherence, the volume of literature focusing on alcohol has begun to increase [4,[25][26][27][28][29][30][31].…”

Section: Alcohol Use and Art Adherencementioning

confidence: 99%

“…Substance use is prevalent among PLWH, cited as one of the correlates of ART nonadherence and associated with medication nonadherence in studies such as Woolf-King et al and Hendershot et al [4,25]. While much of the literature has focused on the association between injection drug use (IDU) and ART adherence, the volume of literature focusing on alcohol has begun to increase [4,[25][26][27][28][29][30][31]. However, the nature, strength, and consistency of the association between alcohol and ART adherence remain unclear [4,25,27].…”

Section: Alcohol Use and Art Adherencementioning

confidence: 99%

“…Despite the effectiveness of treatment as prevention approaches (TasP) such as antiretroviral therapy (ART) in reducing the transmission of HIV, substantial evidence suggests that Black MSM in the U.S. are less likely to adhere optimally to ART compared to other MSM [1][2][3]. One documented factor associated with ART nonadherence among people with HIV (PWH) is heavy alcohol use [4]. While the rates of alcohol use among MSM in the U.S. are high, only a little week evidence suggests that rates of alcohol use are higher among Black MSM-including those in the South-than among their counterparts [5][6][7][8].…”

Section: Introductionmentioning

confidence: 99%

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The Relationship of Alcohol to ART Adherence Among Black MSM in the U.S.: Is it Any Different Among Black MSM in the South?

et al. 2021

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Alcohol-using Black MSM (Men who have sex with men) are disproportionately impacted by HIV in the U.S.—particularly in the southern U.S.—despite the availability of antiretroviral therapy (ART). The purpose of this study was to summarize the current evidence on alcohol use and ART adherence among Black MSM in the U.S. and in the South and to identify future research needs. A systematic review was conducted using eight databases to identify relevant peer-reviewed articles published between January 2010 and April 2021. The authors also snowballed remaining studies and hand-searched for additional studies. Including both quantitative and qualitative studies, five published studies examined alcohol and ART adherence among Black MSM in the U.S. The search identified 240 articles, the study team reviewed 114 in full-text and determined that only five met the inclusion criteria. Three of the five included studies identified alcohol use as a barrier to ART adherence. In conclusions, the general lack of literature on HIV disparities among alcohol-using Black MSM in the U.S. (specifically in the South) indicates a critical need for research on this population’s unique risks and needs to inform the development of tailored interventions.

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Section: Alcohol Use and Art Adherencementioning

confidence: 99%

Section: Alcohol Use and Art Adherencementioning

confidence: 99%

Section: Alcohol Use and Art Adherencementioning

confidence: 99%

Section: Alcohol Use and Art Adherencementioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

The Relationship of Alcohol to ART Adherence Among Black MSM in the U.S.: Is it Any Different Among Black MSM in the South?

et al. 2021

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Alcohol-Antiretroviral Therapy Interactive Toxicity Beliefs and Intentional Medication Nonadherence: Review of Research with Implications for Interventions

El-Krab

Kalichman

2021

AIDS Behav

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Development of a Telephone-Delivered Acceptance and Commitment Therapy Intervention for People Living with HIV who are Hazardous Drinkers

et al. 2022

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Alcohol use among people living with HIV (PWH) has been increasingly recognized as an important component of HIV care. Transdiagnostic treatments, such as Acceptance and Commitment Therapy (ACT), that target core processes common to multiple mental health and substance-related problems, may be ideal in HIV treatment settings where psychological and behavioral health comorbidities are high. In advance of a randomized clinical trial (RCT), the overall objective of this study was to systematically adapt an ACT-based intervention originally developed for smoking cessation, into an ACT intervention for PWH who drink at hazardous levels. Consistent with the ADAPT-ITT model, the adaptation progressed systematically in several phases, which included structured team meetings, three focus group discussions with PWH (N = 13), and in-depth interviews with HIV providers (N = 10), and development of standardized operating procedures for interventionist training, supervision, and eventual RCT implementation. The procedures described here offer a template for transparent reporting on early phase behavioral RCTs.

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A conceptual model of alcohol use and adherence to antiretroviral therapy: systematic review and theoretical implications for mechanisms of action

Cited by 13 publications

References 117 publications

The Relationship of Alcohol to ART Adherence Among Black MSM in the U.S.: Is it Any Different Among Black MSM in the South?

The Relationship of Alcohol to ART Adherence Among Black MSM in the U.S.: Is it Any Different Among Black MSM in the South?

Alcohol-Antiretroviral Therapy Interactive Toxicity Beliefs and Intentional Medication Nonadherence: Review of Research with Implications for Interventions

Development of a Telephone-Delivered Acceptance and Commitment Therapy Intervention for People Living with HIV who are Hazardous Drinkers

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