“…These domains have been used to fingerprint PKS genes from individual strains (Edlund, Loesgen, Fenical, & Jensen, 2011) and environmental DNA (Wawrik et al, 2007). KS phylogeny has even been used to predict secondary metabolite diversity (Foerstner, Doerks, Creevey, Doerks, & Bork, 2008; Metsa-Ketela et al, 1999), structures (Freel, Nam, Fenical, & Jensen, 2011; Gontang, Gaudencio, Fenical, & Jensen, 2010), and the evolutionary processes that generate new structural diversity (Freel et al, 2011)…”