“…Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a complex pathology, and was recently reviewed in [ 1 ]. ME/CFS must be considered a serious and long-term syndrome, which is characterized by fatigue and debilitating muscular–skeletal pain, conditions that affect many fundamental aspects of people’s social habits [ 2 , 3 , 4 ]. Fatigue is a major symptom in ME/CFS and its treatment is accounted for in many forerunners in Italy [ 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 ].…”