A comprehensive study on neurobehavior, neurotransmitters and lymphocyte subsets alteration of Chinese manganese welding workers

Monoamine oxidase activity in placenta in relation to manganese, cadmium, lead, and mercury at delivery

“…Knowing that Mn actively crosses over the placenta [1] and cord blood Mn concentrations are 3-fold higher than in adults, it is difficult to compare the findings reported in environmentally adults with these in newborns. Our results are in agreement with recently reported increase of serotonine metabolite in urine from Mn exposed workers [30].…”

“…Recent epidemiological studies using biomarkers such as prolactine in adults and newborns [28,29], blood [14] and urine monoamines metabolites [30], and MAO-B and dopamine beta-hydroxylase in exposed adult subjects [31] were consistent with mechanistic hypotheses. However, few studies explored MAO as potential biomarker in general population.…”

Neuropsychological testing for the assessment of manganese neurotoxicity: A review and a proposal

“…The numerals in the column heading refer to the following references: 1, Roels et al [1987]; 2, Wennberg et al [1991]; 3, Roels et al [1992]; 4, Chia et al [1993];5, Mergler et al [1994];6, Lucchini et al [1995];7, Sjogren et al [1996]; 8, Gibbs et al [1999]; 9, Lucchini et al [1999]; 10, Deschamps et al [2001];11, Bouchard et al [2003]; 12, Myers et al [2003a]; 13, Myers et al [2003b];14, Bast-Pettersen et al [2004]; 15, Kim et al [2005]; 16, Yuan et al [2006]; 17, Bowler et al [2006];18, Bowler et al [2007]. X, positive results; (X), borderline results.…”

“…The Benton Visual Retention [Benton, 1983] is designed to assess visual perception, visual memory, and visual-constructive abilities. It was administered in five studies, with positive results in the studies by Bast-Pettersen et al [2004] and Yuan et al [2006]. Chia et al [1993] and Myers et al [2003b] observed instead significant differences between exposed workers and control group.…”

Biomarkers of Occupational Manganese Toxicity

“…However, experimental studies on laboratory animals have reported similar results, but studies in human societies have reported conflicting results [23][24] . The use of manganese concentrations in the blood has been studied as a biomarker of exposure to manganese among welders, metal workers, miners and workers making dry batteries [25][26][27][28][29][30][31][32][33][34][35][36] . In general, these studies revealed that the concentration of blood manganese as an acceptable index is also reflected in the comparison group in the face of active and current exposure and it is the most common indicator used to compare groups and the control group.…”