A comprehensive study of the effect of drying methods on compounds in Elaeagnus angustifolia L. flower by GC-MS and UHPLC-HRMS based untargeted metabolomics combined with chemometrics

Zhang, Jia-Ni; Ma, Meng-Han; Ma, Xing-Ling; Ma, Fenglian; Du, Qing-Yu; Liu, Jianan; Wang, Xing-Cai; Zhao, Qipeng; Ya, YU; She, Yuanbin

doi:10.1016/j.indcrop.2023.116452

Cited by 6 publications

(3 citation statements)

References 35 publications

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“…As shown in Figure 4A, peaks 1 and 2 presented characteristic MS 2 fragment ions at m/z 115 and 111, respectively, resulting from the loss of a water molecule from malic acid and the absence of a water molecule as well as a CO 2 group from citric acid, which had been verified by Oldoni et al (28). These compounds had also been reported in apple (29), grape (30) and Elaeagnus angustifolia L. flower (31). It is worth noting that malic acid and citric acid are the important intermediates of the tricarboxylic acid cycle, which participate in regulating the metabolism of sugars, fatty acids and amino acids (32).…”

Section: Organic Acidssupporting

confidence: 59%

“…In addition, peak 13 also presented characteristic MS 2 fragment ions at m/z 152 [M-H-CH 3 ] − and 108 [M-H-CO 2 -CH 3 ] − , suggesting peak 13 was vanillic acid according to a previous report in ribes stenocarpum by Jiang et al (33). The MS 2 fragment ions of peak 18 further showed characteristic MS 2 fragment ions at m/z 182 and 166, resulting from the loss of-CH 3 (15) and -OCH 3 (31) in negative ion mode, respectively, in the structures, which presented a characteristic fragmentation behavior of syringic acid (35).…”

Section: Organic Acidsmentioning

confidence: 54%

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Characterization, antioxidant and antitumor activities of phenolic compounds from Amomum villosum Lour.

Zhang,

Shuai,

Wei

et al. 2024

Front. Nutr.

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Amomum villosum Lour. (A. villosum), known as Sharen in China, is widely used for culinary and medicinal purposes due to containing a diverse set of bioactive compounds. In this study, the optimum ethanol extraction process was optimized and the composition and biological activities (antioxidant and antitumor) of five different fractions (dichloromethane, petroleum ether, ethyl acetate, n-butanol and H2O) extracted from the ethanol extract of A. villosum were investigated. The results showed that the optimal extraction conditions were extraction temperature 80°C, extraction time 120 min, ethanol concentration 40% and solid–liquid ratio 1:25 g/mL. Moreover, 35 bioactive compounds were successfully identified by UPLC-ESI-QTOF-MS/MS from five factions for the first time, including 12 phenolic acids and derivatives, 2 organic acids, 12 flavonoids and derivatives, 2 oxylipins and 7 proanthocyanidins. Among them, ethyl acetate fraction (Fr-EtOAc) exhibited the highest content of total phenolic (374.01 mg GAE/g DW) and flavonoid (93.11 mg RE/g DW), where vanillic acid, catechin, epicatechin and protocatechuic acid were the predominant phenolic compounds that accounting for 81.65% of the quantified bioactive compounds. In addition, Fr-EtOAc demonstrated excellent total antioxidant activity (IC50 of DPPH and ABTS assays were 0.23, 0.08 mg/mL, respectively, and FRAP assay was 322.91 mg VCE/100 g DW) and antitumor activity (1,000 μg/mL, 79.04% inhibition rate). The results could provide guidance for the industrial production and application of A. villosum.

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Section: Organic Acidssupporting

confidence: 59%

Section: Organic Acidsmentioning

confidence: 54%

Characterization, antioxidant and antitumor activities of phenolic compounds from Amomum villosum Lour.

Zhang,

Shuai,

Wei

et al. 2024

Front. Nutr.

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“…For example, the flowers of E. angustifolia L. were used for thoracalgia and asthma in Chinese Uygur medicine [ 2 ]. In addition, Elaeagnus plants contain a myriad of bioactive compounds [ 3 , 4 ], such as flavonoids, phenolic carboxylic acids, polyphenols, terpenoids, alkaloids, and steroids, responsible for the significant biological characteristics of plants, including antioxidant, antibacterial, analgesic, and anti-inflammatory effects [ 5 , 6 ].…”

Section: Introductionmentioning

confidence: 99%

Green Extraction of Polyphenols from Elaeagnus angustifolia L. Using Natural Deep Eutectic Solvents and Evaluation of Bioactivity

Li,

Lv,

Wang

et al. 2024

Molecules

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In the study, natural deep eutectic solvents (NADESs) were used as alternatives to traditional chemical solvents for the extraction of polyphenols from Elaeagnus angustifolia L. Nine NADESs were tested for the first time and compared with ethanol and water (traditional solvents) regarding the extraction of phenolic compounds from E. angustifolia L. These solvents were particularly effective at extracting polyphenols, whose low water solubility usually requires high amounts of organic solvents. The solvent based on choline chloride and malonic acid provided optimal results and was selected for further optimization. The effects of material-to-liquid ratio, ultrasound time, and ultrasound temperature on the extraction efficiency were studied through single-factor experiments. These parameters were optimized by Box–Behnken design using response surface methodology. The optimal conditions identified were 49.86 g/mL of material-to-liquid ratio, 31.10 min of ultrasound time, and 62.35 °C of ultrasound temperature, resulting in a high yield of 140.30 ± 0.19 mg/g. The results indicated that the NADES extraction technique provided a higher yield than the conventional extraction process. The antioxidant activity of the extract of polyphenols from E. angustifolia L. was determined, and UPLC–IMS–QTOF–MS was used to analyze the phenolic compounds in it. The results revealed that the scavenging ability of 1,1-diphenyl-2-picryl-hydrazil and 2,2′-azinobis-(3-ethylbenzthiazoline-6-sulphonate) extracted by NADES was higher than that of polyphenols extracted by water and ethanol. Furthermore, a total of 24 phenolic compounds were identified in the extract. To the best of our knowledge, this is the first study in which a green and efficient NADES extraction method has been used to extract bioactive polyphenols from E. angustifolia L., which could provide potential value in pharmaceuticals, cosmetics, and food additives.

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Combining with volatilomic profiling and chemometrics to explore the volatile characteristics in five different dried Zanthoxylum bungeanum maxim

Feng,

Hao,

Zhu

et al. 2024

Food Research International

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A comprehensive study of the effect of drying methods on compounds in Elaeagnus angustifolia L. flower by GC-MS and UHPLC-HRMS based untargeted metabolomics combined with chemometrics

Cited by 6 publications

References 35 publications

Characterization, antioxidant and antitumor activities of phenolic compounds from Amomum villosum Lour.

Characterization, antioxidant and antitumor activities of phenolic compounds from Amomum villosum Lour.

Green Extraction of Polyphenols from Elaeagnus angustifolia L. Using Natural Deep Eutectic Solvents and Evaluation of Bioactivity

Combining with volatilomic profiling and chemometrics to explore the volatile characteristics in five different dried Zanthoxylum bungeanum maxim

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