A comprehensive review on the phytoconstituents and biological activities of Nyctanthes arbor-tristis L.

Abstract

Nyctanthes arbor-tristis (NAT) is one of the Indonesian herbal medicines which belongs to the genus Nyctanthes and the Oleaceae family. Traditionally, NAT is used to reduce fever and pain and treat hemorrhoids, irregular menstruation, cough, and asthma. This review article aimed to examine the phytoconstituents and pharmacological activities of NAT from different plant parts. The literature search was conducted through PubMed and Google Scholar databases. Our literature study showed that NAT has various secondary metabolites, such as steroids, terpenes, flavonoids, phenol, iridoid glycosides, and alkaloids. These compounds are distributed in the leaves, seeds, flowers, and stem bark. Different chemical structures of secondary metabolites are present in each plant part, and each demonstrates distinct pharmacological activities. The most common activities found in the literature are antimicrobial, analgesic, antiinflammatory, antidiabetic, antioxidant, hepatoprotective, antitussive, and antimalarial activities. Although this plant offers a promising source for drug discovery, the pharmacological and phytochemical data are still limited. Further studies are needed to explore the potency of NAT as natural products benefiting human health.

Genomic and Transcriptomic Analyses Illuminates Unique Traits of Elusive Night Flowering Jasmine Parijat (Nyctanthes arbor‐tristis)

“…Terpenoids and carotenoids, followed by benzenoids, dominate the volatile components of the flower (Siriwardena and Arambewela 2014; Borghi et al, 2017). Flavonoids and alkaloids are also major constituents of Parijat (Dewi et al, 2022). The Orange pedicels of the Parijat flower contain an abundance of crocin, an important constituent of the Saffron ( Crocus sativus ) calyx.…”

“…Parijat has a multitude of medicinal and economic applications due to biological activities like anti‐bacterial, anti‐viral, anti‐inflammatory, antioxidant, immunomodulatory, anti‐fungal, and anti‐ageing properties and is extensively used to treat skin conditions and arthritis. Parijat produces large amounts of secondary metabolites like alkaloids, terpenoids, saponins, phenolics, phytosterols, and tannins with various industrial applications (Parekh and Soni 2020; Dewi et al, 2022). Parijat has a high repurposing potential, but due to the lack of genetic and experimental studies, it has remained undervalued.…”

Review on Nyctanthes Arbortristis

“…The chloroform extract of the flowers and a pure compound isolated from Nyctanthesarbortristis plant exhibit larvi-Cidal activity against Culex quinquefasciatus Say, a common filarial vector.The free radical scavenging potential Of the different extracts of leaves of Nyc-Tanthesarbortristis was evaluated invitro [18,37] f. Anti-Oxidant activity By employing diphenyl-picryl-hydrazy(DPPH) assay method. In this investigation The antioxidant which present in the plant Extracts reacted with DPPH, which is a Stable free radical and converted it to 1, 1-Diphenyl -1, 2-picryl, hydrazine which was Measured at 517 nm.…”

Evaluation of the Antithrombotic Activity of Acmella oleracea L. Flower Ethanol Extract

“…Specifically, Indonesia has many medicinal plants with various pharmacological activities, such as antioxidant, antimalarial, antiproliferative, anti-inflammatory, anticancer, antidiabetic, anticoagulant, antiplatelet, antithrombotic, and many more. [4][5][6][7][8] Therefore, developing and discovering new antithrombotic agents is still needed from various sources, including Indonesian medicinal plants. One of the herbal plants widely known as an annual herb is Acmella oleracea (hereinafter abbreviated as AOE).…”