A comprehensive review on tannase: Microbes associated production of tannase exploiting tannin rich agro-industrial wastes with special reference to its potential environmental and industrial applications

Construction of a Tannase-Immobilized Magnetic Graphene Oxide/Polymer Nanobiocatalyst with Enhanced Enzyme Stability for High-Efficiency Transformation of Tannins

“…The abundance of tannins in plant tissues and their potential bioconversion into sustainable chemicals such as gallic acid have attracted great attention in biotechnological fields for maximum utilization of natural compounds. − Tannins offer protection to the plants against microbial damage. Due to the presence of high amounts of tannins, tea, fruit juices, beverages, and dry fruits are astringent, hazy, and bitter, which lead to unpleasant flavors for humans. − In addition, tannin is one of the major components of effluents discharged by tanning industries, which poses potential threat to human health and aquatic organisms. , Hence, tannin treatment is a requisite for health and industrial aims.…”

“…Despite the previously mentioned benefits, the enzyme-catalyzed transformation of tannin using tannase still faces several key challenges. For example, the complicated purification process, high production cost, insufficient enzyme stability, limited enzyme selectivity or specificity, low tolerance in the presence of inhibitors, finite application conditions, and inability to recycle after every use of free forms make this approach unsustainable for the long-term usage in industrial applications. , In this situation, immobilization of enzymes on a solid support is regarded as an effective strategy to overcome the above-mentioned limitations. − Stable supports for tannase immobilization include calcium alginate beads, − chitosan, manganese nanoparticles, magnetic nanoparticles, multiwalled carbon nanotubes, and silica oxide nanoparticles . The immobilization yield and reusability have been improved to a certain extent, but some major drawbacks remain.…”

Production of tannase and gallic acid by three fungal strains under submerged fermentation using agricultural waste

“…Tannase applications are diversified among food, pharmaceuticals and rations industries. Other uses of tannase might include leather tanning, instant tea manufacturing and clarifying agent for juices, beers, some wines and sodas that have coffee as component [20].…”

Biochemical and Structural Characterization of a Novel Bacterial Tannase From Lachnospiraceae bacterium in Ruminant Gastrointestinal Tract

“…Exceptionally, TanB SS encoded by a tanB gene from Streptomyces sviceus was identified as an extracellular tannase ( Wu et al, 2014 ). The optimum temperature and pH value for biochemical characteristics of bacterial tannases are 30°C–50°C and 3.0–7.0, respectively ( Lekshmi et al, 2021 ). Up to now, two kinds of bacterial tannase belonging to probiotics (TanA Lp , Lactobacillus plantarum ) and the oral bacteria (TanB Fnn , Fusobacterium nucleatum ) have been structurally characterized by combining crystal structure, molecular dynamics, and mutation analysis, which confirmed the functional role of the flap domain and flap-like domain in the substrate recognition and specificity of tannase ( Ren et al, 2013 ; Mancheño et al, 2020 ).…”