A comprehensive review on phytochemical and pharmacological aspects of Elaeagnus angustifolia L.

Abstract

Objective Elaeagnus angustifolia L., commonly known as oleaster or Russian olive, is used worldwide as a traditional natural remedy or nutritional agent for the management of a wide range of illnesses. The aim of the present study is to comprehensively review the ethnopharmacological uses, biological activities and phytochemistry of E. angustifolia. Key findings Modern scientific investigations suggest that the plant possesses a broad spectrum of pharmacological and therapeutic effects, including antimicrobial, insecticidal, antioxidant, anti-arthritic, wound healing, cardioprotective, hypolipidemic, antinociceptive, anti-inflammatory, antimutagenic, antitumour and gastroprotective activity. Various phytochemical constituents, including β-carboline alkaloids, polysaccharides, esters, flavone glycosides, phenols, phenolic acids, ketones, phenyl ethers, pyrimidines, steroids and terpenes, as well as nutritional components such as essential and non-essential amino acids and nutraceuticals like vitamins and fatty acids, have been identified in E. angustifolia. Summary Considering its wide variety of pharmacological activity as well as its huge diversity of active phytochemicals, E. angustifolia could be proposed as a good candidate for discovering new drugs. Further clinical and experimental studies are necessary to reveal the beneficial therapeutic, safety and pharmaceutical properties of E. angustifolia and its phytochemicals as a complementary and alternative medicine for the management of various disorders.

ISOLATION AND CHARACTERIZATION OF Β-Sitosterol FROM ELAEAGNUS ANGUSTIFOLIA CULTIVATED IN IRAQ

“…Plants belonging to this genus are famous for its medical benefits. Recent pharmacological studies have shown that E. angustifolia L. has anti-inflammatory, antimicrobial, antioxidant, antitumor, and cardiovascular effect [5]. A large number of phytochemical components have been derived from Russian olive and made this plant a source of flavonoids, alkaloids, saponin ,terpens and complicated sterols and sterols [6] as shown in Fig.…”

Essential Oil from Flowers and Leaves of Elaeagnus Angustifolia (Elaeagnaceae): Composition, Radical Scavenging and General Toxicity Activities

“…7 Some of them were proven to exhibit anti-inflammatory, 1,8 muscle relaxant activity, 9 anti-ulcerogenic, 10 antimicrobial, [11][12][13][14] antinociceptive, 15,16 antitumor, 17,18 and antioxidant effects. 11,12,14,[19][20][21] Likewise, the whole fruit and medulla powder of E. angustifolia showed positive effect in improving pain, stiffness and physical function in women with osteoarthritis of the knee. 22,23 In Azarbaijan province folk medicine, the fruit and flower preparations have been used for healing jaundice, asthma, flatulence, vomiting and nausea.…”

“…24 Phytochemical studies on different extracts from fruits and flowers of E. angustifolia indicated the presence of polysaccharides, flavonoids, coumarins, phenolcarboxylic acids, amino acids, saponins, carotenoids, vitamins, and tannins as secondary metabolites. 12,13,25 Besides mentioned secondary metabolites, this plant also contains volatile oils that may be useful as a source of nutrition or pharmaceutical compounds. [26][27][28] To the best of our knowledge, the essential oil composition of the Iranian E. angustifolia has not been investigated; therefore, based on the prevalent food and medicinal uses of this plant, the present study was conducted to analyze the chemical composition of the essential oils hydrodistilled from the leaves and flowers of E. angustifolia as well as their general toxicity and radical scavenging activities.…”

The Caucasian flora: a still-to-be-discovered rich source of antioxidants

“…In another plant endemic to Georgia, P. spinosa L., the amount of phenols again differed according to the area of cultivation and ranged from 331.0 mg to 114.9 mg/100 g. Antioxidant activity was somewhere around 25.11 mg. As for Georgian tangerines, the total amount of phenols varied between 0.364 mg and 0.474 mg/ml (in juice). The highest value radical scavenging activity among the samples was found in the tangerines Tiaxara Unshiu (80.05 mg) and Iwasaki (74.45 mg), with lower activities in samples of Mukoiyama and Clemenules, that is, 79.9-191.72 mg (Figure 2) [44,45].…”