A Comprehensive Review on Pemphigus Vulgaris

Handa, H

doi:10.26717/bjstr.2017.01.000552

Cited by 2 publications

(1 citation statement)

References 14 publications

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“…It is a rare condition [0.1-0.5 cases per 100,000 people per year] with symptoms appearing in the fifth or sixth decade of life. PV affects both men and women equally and has a strong genetic and environmental association [1,2]. Systemic corticosteroids, particularly prednisolone, are the drug of choice for the treatment of PV disease.…”

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confidence: 99%

An Analysis of Prescription Pattern, Adherence to Pharmacotherapy and Quality of Life in Pemphigus Vulgaris Patients

HIRAPARA,

SINGH,

KARELIA

et al. 2024

Int J Pharm Pharm Sci

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Objective: Pemphigus Vulgaris [PV] is a chronic autoimmune disease. Corticosteroids and Immunosuppressants are the main line of treatment. The aim of this study was to evaluate the prescription pattern and patient adherence behavior with therapy. We determined the association between patient adherence and quality of life in patients with pemphigus vulgaris. Methods: A prospective observational study was conducted from February 2020 to May 2021. The age and sex of patients who were diagnosed with PV within 1 mo period and confirmative histopathological findings in Biopsy were included in the study. A total of 35 patients were analyzed and patients were reviewed for medication adherence and quality of life by using MMAS-8 and WHOQOL respectively, monthly till 3 mo after initiation of therapy. Statistical analysis was done by using Epi Info version 7.1.5. Results: Out of 140 prescriptions, vitamin C and zinc were the most common drug prescribed in 129 prescriptions followed by prednisolone prescribed in 128 prescriptions. The average number of drugs per encounter was 8.67. 97.56 % of drugs were prescribed by generic names. No significant improvement was seen in the adherence behavior of patients from 1st follow-up to 3rd follow-up. It was observed that physical, psychological, and environmental domains have significant associations with medication adherence in all 3 follow-up visits. Conclusion: It was concluded that Polypharmacy and inappropriate use of medicines may decrease the adherence behavior of patients to the therapy. Low adherence to pharmacotherapy affects the quality of life in PV patients. This study is beneficial for raising awareness about treatment adherence and also encouraging the development of appropriate interventions.

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Section: Introductionmentioning

confidence: 99%

An Analysis of Prescription Pattern, Adherence to Pharmacotherapy and Quality of Life in Pemphigus Vulgaris Patients

HIRAPARA,

SINGH,

KARELIA

et al. 2024

Int J Pharm Pharm Sci

View full text Add to dashboard Cite

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Haemato-Biochemcial Studies of Nanoparticle-Based Vaccine Against R2b Strain of New Castle Disease in Chicks

TOMAR,

YADAV,

CHAUHAN

2024

Int J Pharm Pharm Sci

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Objective: The goal of the current study is to create a Newcastle disease vaccine based on green synthesised metal oxide nanoparticles and to study the haematological and biochemical effects of this vaccine in chicks. Methods: Copper Oxide Nanoparticles (CuONPs) from Momordica charantia were synthesised biologically. These copper oxide nanoparticles were combined with a commercially available freeze-dried Newcastle Di0sease (ND) vaccination of the live R2B strain to use it as a vaccine delivery method in the current work. Haematological and biochemical parameters were investigated in pre-challenged and post-challenged chicks. Results: After the injection of copper nanoparticles-based vaccines, it was found that the pre-challenged animals and post challeneged animals showed highly significant difference (P<0.05) in their total White Blood Cells (WBC) counts, hemoglobin concentration, hematocrit value, and Erythrocyte Sedimentation Rate (ESR) in comparison to control and live vaccinated groups. It was also investigated that for biochemical parameters After the injection of copper nanoparticles-based vaccines, both pre-challenged animals and post challeneged animals showed highly significant difference (P<0.05) in their blood glucose level, serum total protein, creatinine, serum alkaline phosphatase, Aspartate Amino Transferase (ALT) and Alanine Amino Transferasse (AST) in comparison to control and live vaccinated groups. Conclusion: The vaccine not only makes chicks healthier, but also shields them from the virus that causes Newcastle disease

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A Comprehensive Review on Pemphigus Vulgaris

Cited by 2 publications

References 14 publications

An Analysis of Prescription Pattern, Adherence to Pharmacotherapy and Quality of Life in Pemphigus Vulgaris Patients

An Analysis of Prescription Pattern, Adherence to Pharmacotherapy and Quality of Life in Pemphigus Vulgaris Patients

Haemato-Biochemcial Studies of Nanoparticle-Based Vaccine Against R2b Strain of New Castle Disease in Chicks

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