A Comprehensive review on Dichrostachys cinerea

Abstract

For a very long time, the medical plants have been used worldwide to treat human diseases and it serves as a safe source of drugs to cure several diseases and conditions through complementary medicine system. It is a native plant of Indian subcontinent, Africa and North Australia and is known to have significant pharmacological activities. The wide range of pharmacological activities of D.cinerea are due to the presence of different groups of active biological compounds present in it. Traditionally, D.cinerea has been used for the treatment the treatment of many diseases such as headache, toothache, dysentery, leprosy, coughs, syphilis and also as diuretic, anthelmintic, purgative and laxative. Research on the pharmacological, biological isolation of metabolites and biologically active compounds of this plant have already been done worldwide. However, the study to evaluate the complete therapeutic values of this plant still needed to conduct. This paper briefly reviews the various pharmacological properties of D.cinerea that could be useful for further experimental and clinical investigations.

Polyphenols from Dichrostachys cinerea Fruits Anti-Inflammatory, Analgesic, and Antioxidant Capacity in Freund’s Adjuvant-Induced Arthritic Rat Model

“…Our previous studies also indicated the analgesic effect of DC fruits water extract, but in a different model of pain (induced by acetic acid) and acute inflammation (induced by carrageenan) that the one presented in this study (induced by CFA) [ 12 ]. Dychrostachis cinerea analgesic effect was also reported in the literature for DC leaf, roots, or bark extracts in different acute inflammatory pain models [ 8 , 42 ], but to our knowledge, there are no references regarding the analgesic effect in chronic pain models.…”

“…It is widespread in Africa and India, and is considered an invasive species in the Caribbean. Dichrostachys cinerea ’s bark, roots, and fruit pods are used in traditional medicine as remedies against common health problems such as fever, pain, and diarrhea, but it also has laxative properties [ 8 ]. It is also used in some populations to prevent sexually transmitted diseases [ 9 , 10 ], for cicatrizing effects [ 11 , 12 ], or as an anti-inflammatory agent [ 13 ].…”

Indigenous Strategies for Managing Bush Encroachment in Rural Areas of South Africa

“…This assertion validates the indigenous knowledge of villagers. Equally, as echoed by the villagers in Mafarana, while the plant has detrimental effects to the environment, grasses, and other surrounding plants, it has proven to also have beneficial uses (i.e., medicinal, animal feed, and firewood, as scientifically corroborated by numerous scholars [36][37][38]). This observation validates the space and need for co-existence of these knowledge systems within society.…”