A comprehensive review of the antibacterial, antifungal and antiviral potential of essential oils and their chemical constituents against drug-resistant microbial pathogens

Tariq, Saika; Wani, Saira; Rasool, Waseem; Shafi, Khushboo; Bhat, Muzzaffar A.; Prabhakar, A. S.; Shalla, Aabid H.; Rather, Manzoor A.

doi:10.1016/j.micpath.2019.103580

Cited by 441 publications

(277 citation statements)

References 213 publications

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“…Additionally, essential oils inhibit the synthesis of fungal DNA, RNA, proteins, and polysaccharides [150]. Essential oils can also disintegrate mitochondrial membrane [151,152]. It has also been shown that essential oil from Thymus vulgaris inhibits the production of aflatoxins by Aspergillus flavus and leads to the reduction of ergosterol production [123].…”

Section: Antifungal Activity Of Essential Oils Of Lamiaceae Familymentioning

confidence: 99%

Essential Oils of Lamiaceae Family Plants as Antifungals

Karpiński

2020

Biomolecules

125

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The incidence of fungal infections has been steadily increasing in recent years. Systemic mycoses are characterized by the highest mortality. At the same time, the frequency of infections caused by drug-resistant strains and new pathogens e.g., Candida auris increases. An alternative to medicines may be essential oils, which can have a broad antimicrobial spectrum. Rich in the essential oils are plants from the Lamiaceae family. In this review are presented antifungal activities of essential oils from 72 Lamiaceae plants. More than half of these have good activity (minimum inhibitory concentrations (MICs) < 1000 µg/mL) against fungi. The best activity (MICs < 100) have essential oils from some species of the genera Clinopodium, Lavandula, Mentha, Thymbra, and Thymus. In some cases were observed significant discrepancies between different studies. In the review are also shown the most important compounds of described essential oils. To the chemical components most commonly found as the main ingredients include β-caryophyllene (41 plants), linalool (27 plants), limonene (26), β-pinene (25), 1,8-cineole (22), carvacrol (21), α-pinene (21), p-cymene (20), γ-terpinene (20), and thymol (20).

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Section: Antifungal Activity Of Essential Oils Of Lamiaceae Familymentioning

confidence: 99%

Essential Oils of Lamiaceae Family Plants as Antifungals

Karpiński

2020

Biomolecules

125

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“…Looking at published data several EOs show antiviral activity against many enveloped RNA and DNA viruses. Among our five EOs, thyme and oregano seems to have more consideration in this field . Only few essential oils, e. g ., oregano oil, were also tested against non‐enveloped RNA and DNA viruses .…”

Section: Essential Oils: Very Old ‘Guys’ With Great Prospectsmentioning

confidence: 99%

“…Among our five EOs, thyme and oregano seems to have more consideration in this field. [354] Only few essential oils, e. g., oregano oil, were also tested against non-enveloped RNA and DNA viruses. [355] Oregano oil and one of its main active component, carvacrol, was assayed against the nonenveloped murine norovirus (MNV), a human norovirus surrogate, demonstrating that carvacrol is effective in inactivating MNV within 1 h of exposure by acting directly on the viral capsid and subsequently the RNA.…”

Section: Eos and Human Healthmentioning

confidence: 99%

New Tricks for Old Guys: Recent Developments in the Chemistry, Biochemistry, Applications and Exploitation of Selected Species from the Lamiaceae Family

Napoli

Siracusa

Ruberto

2020

Chemistry & Biodiversity

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Lamiaceae is one of the largest families of flowering plants comprising about 250 genera and over 7,000 species. Most of the plants of this family are aromatic and therefore important source of essential oils. Lamiaceae are widely used as culinary herbs and reported as medicinal plants in several folk traditions. In the Mediterranean area oregano, sage, rosemary, thyme and lavender stand out for geographical diffusion and variety of uses. The aim of this review is to provide recent data dealing with the phytochemical and pharmacological studies, and the more recent applications of the essential oils and the non‐volatile phytocomplexes. This literature survey suggests how the deeper understanding of biomolecular processes in the health and food sectors as per as pest control bioremediation of cultural heritage, or interaction with human microbiome, fields, leads to the rediscovery and new potential applications of well‐known plants.

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“…Among the Thymus species, Thymus vulgaris L. (commonly known as thyme) is widely used as aromatic and medicinal plant in food, agriculture, pharmaceutical, and cosmetic industries. Thyme EO possesses strong antibacterial and fungicidal activities, being rich in oxygenated monoterpenes and hydrocarbon monoterpenes: thymol, carvacrol, p-cymene and γ-terpinene [11,[98][99][100].…”

Section: Thyme Essential Oilmentioning

confidence: 99%

Electrospinning of Essential Oils

Mele

2020

Polymers

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The extensive and sometimes unregulated use of synthetic chemicals, such as drugs, preservatives, and pesticides, is posing big threats to global health, the environment, and food security. This has stimulated the research of new strategies to deal with bacterial infections in animals and humans and to eradicate pests. Plant extracts, particularly essential oils, have recently emerged as valid alternatives to synthetic drugs, due to their properties which include antibacterial, antifungal, anti-inflammatory, antioxidant, and insecticidal activity. This review discusses the current research on the use of electrospinning to encapsulate essential oils into polymeric nanofibres and achieve controlled release of these bioactive compounds, while protecting them from degradation. The works here analysed demonstrate that the electrospinning process is an effective strategy to preserve the properties of essential oils and create bioactive membranes for biomedical, pharmaceutical, and food packaging applications.

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A comprehensive review of the antibacterial, antifungal and antiviral potential of essential oils and their chemical constituents against drug-resistant microbial pathogens

Cited by 441 publications

References 213 publications

Essential Oils of Lamiaceae Family Plants as Antifungals

Essential Oils of Lamiaceae Family Plants as Antifungals

New Tricks for Old Guys: Recent Developments in the Chemistry, Biochemistry, Applications and Exploitation of Selected Species from the Lamiaceae Family

Electrospinning of Essential Oils

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