A Comprehensive Review of Protein Biomarkers for Invasive Lung Cancer
Alexandre Mezentsev,
Mikhail Durymanov,
Vladimir A. Makarov
Abstract:Invasion and metastasis are important hallmarks of lung cancer, and affect patients’ survival. Early diagnostics of metastatic potential are important for treatment management. Recent findings suggest that the transition to an invasive phenotype causes changes in the expression of 700–800 genes. In this context, the biomarkers restricted to the specific type of cancer, like lung cancer, are often overlooked. Some well-known protein biomarkers correlate with the progression of the disease and the immunogenicity… Show more
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