A comprehensive review of computational cell cycle models in guiding cancer treatment strategies
Chenhui Ma,
Evren Gurkan-Cavusoglu
Abstract:This article reviews the current knowledge and recent advancements in computational modeling of the cell cycle. It offers a comparative analysis of various modeling paradigms, highlighting their unique strengths, limitations, and applications. Specifically, the article compares deterministic and stochastic models, single-cell versus population models, and mechanistic versus abstract models. This detailed analysis helps determine the most suitable modeling framework for various research needs. Additionally, the… Show more
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