A comprehensive review of 3D cancer models for drug screening and translational research
Karthikey Sharma,
Sreenath Dey,
Rounik Karmakar
et al.
Abstract:The 3D cancer models fill the discovery gap of 2D cancer models and play an important role in cancer research. In addition to cancer cells, a range of other factors include the stroma, density and composition of extracellular matrix, cancer‐associated immune cells (e.g., cancer‐associated fibroblasts cancer cell‐stroma interactions and subsequent interactions, and a number of other factors (e.g., tumor vasculature and tumor‐like microenvironment in vivo) has been widely ignored in the 2D concept of culture. De… Show more
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