A Comprehensive Literature Review of COPD-Related Fatigue

Lewko, Agnieszka; Bidgood, Penelope; Jewell, Andrew P.; Garrod, Rachel

doi:10.2174/157339812803832476

Cited by 18 publications

(11 citation statements)

References 47 publications

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“…Our results showed that the financial factor as a social factor emerged in three dimensions that measured quality of life of the COPD patients, while the grade of COPD emerged as a statistically significant predictor of all four dimensions of this questionanaire. Similarly to our results, it was reported that the decrease of financial status was one of the main reasons for patients' feelings of being unable to fulfill their life goals 17,18 . It was reported that the lower social class in terms of the financial status had lower levels of QoL 17,[19][20][21] .…”

Section: Discussionsupporting

confidence: 90%

Predictors of quality of life of patients with chronic obstructive pulmonary disease

et al. 2019

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Background/Aim. Chronic obstructive pulmonary disease (COPD) has a significant impact on quality of life of patients. We investigated which demographic and social characteristics can predict the global quality of life (QoL) of COPD patients. Methods. The patients (n = 288) were divided into three groups according to the stage of disease: Group I = stage 0-at risk; Group II = Stages I and II; Group III = stages III and IV. The patients fulfilled a questionnaire related to the demographic and social characteristics and the validated multidimensional questionnaire-Serbian version of the St. George's Respiratory Questionnaire (SGRQ). The Student's t test, χ² test, ANOVA, univariate and multivariate logistic regression tests were used for statistical analyses. Results. In the group I, prevailed the men, employed persons, with a moderate financial status and no family history of COPD. In the group II dominated women, pensioners, with a moderate financial status, duration of illness up to five years, and no family history of COPD. In the group III prevailed women, unemployed persons, a moderate financial status, COPD duration up to 5 years and Ključne reči: pluća, opstruktivne bolesti, hronične; kvalitet života; demografija; socijalno-ekonomski faktori; ankete i upitnici; srbija.

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Section: Discussionsupporting

confidence: 90%

Predictors of quality of life of patients with chronic obstructive pulmonary disease

et al. 2019

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“…Subjective fatigue is an important and highly prevalent symptom in Chronic Obstructive Pulmonary Disease (COPD) [1]. People with COPD experience greater fatigue than healthy older people [2e4] and this, in turn, is associated with the severity of the disease rather than age itself.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of multidimensional COPD-related subjective fatigue following a Pulmonary Rehabilitation programme

Lewko

Bidgood

Jewell

et al. 2014

Respiratory Medicine

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Introduction: Subjective fatigue has been recognised as an important, multi-component symptom in COPD. Pulmonary Rehabilitation (PR) improves fatigue component of the Chronic Respiratory Questionnaire, a quality of life (QoL) measure. However, it is not clear if all fatigue dimensions are affected equally. This study aims to evaluate changes in subjective multidimensional fatigue among people with COPD who participated in PR. Methods: Thirty seven stable COPD patients were recruited; 23 patients (15 male) mean age 68.5 (range 49e86) yrs, mean (SD) %predicted FEV 1 45.3 (19.8); completed 7 weeks of PR. Assessments (pre and post PR) consisted of the Multidimensional Fatigue Inventory (MFI-20), QoL (SGRQ), Anxiety and Depression (HADS), the London Chest Activity of Daily Living Scale (LCADL), muscle strength, incremental (ISWT) and endurance (ESWT) shuttle walk tests. The differences between pre and post PR fatigue were tested using Wilcoxon's test and relationships with other outcomes were examined using Spearman's correlation. Results: There were statistically significant improvements in Reduced Activity (RA) (p Z 0.01), General (GF) (p < 0.01) and Physical Fatigue (PF) (p Z 0.03) components of MFI-20 after PR, but there were no differences in Motivation or Mental Fatigue (p > 0.05). There were significant improvements in ISWT (p < 0.05), ESWT (p < 0.01) and muscle strength (p Z 0.03). Statistically significant correlations (p < 0.05) were found between changes in GF and in both ISWT (r Z À0.43) and SGRQ impact (r Z 0.46); and between RA and ESWT changes (r Z À0.45).

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“…According to the CRQ was fatigue the problem affecting the patients' HRQoL most. Fatigue is a cardinal but multifaceted symptom of advanced COPD and described as a profound feeling of physical and psychological wariness that is not relieved by sleep or rest [11,26]. Studies report fatigue prevalences in patients with advanced COPD to 71 and 96% in palliative patients [26].…”

Section: Discussionmentioning

confidence: 99%

Characteristics and health related quality of life in a population with advanced chronic obstructive pulmonary disease, a cross-sectional study

2020

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Background: It is important to understand the total burden of COPD and thereby be able to identify patients who need more intensive palliative care to avoid deteriorated quality of life. The aim of this study was to describe the psychosocial and demographic characteristics of a population with advanced COPD in a stable phase of the disease. Methods: This study was cross-sectional based on a prospective observational cohort. The following questionnaires were administered: Chronic Respiratory Disease Questionnaire (CRQ), The COPD Assessment Test (CAT), The Hospital and Anxiety and Depression Scale (HADS), The Medical Research Council dyspnoea scale (MRC), and self-rate general health. Results: We included 242 patients with advanced COPD from a Danish pulmonary outpatient clinic. Their mean FEV 1 was 38% (±12.7) and 19% were treated with long term oxygen. The mean CRQ domain score was CRQdyspnea 4.21 (±1.4), CRQ-Mastery 4.88 (±1.3), CRQ-Emotional 4.81 (±1.2), CRQ-Fatigue 3.93 (±1.3). The mean CATscore was 18.4 (± 6.7), and 44% had a CAT score > 20. The mean score on the subscale for anxiety (HADS-A) and depression (HADS-D) was 5.07 (±3.9) and 5.77 (±3.9), respectively. Thirty percent self-rated their health as bad or very bad and 19.8% were current smokers. Conclusions: This study describes the characteristics of a population with advanced COPD in a stable phase of their disease. Our results illustrate how the population although treated in an outpatient structure already focusing on palliative needs, still live with unmet palliative needs and impaired quality of life.

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A Comprehensive Literature Review of COPD-Related Fatigue

Cited by 18 publications

References 47 publications

Predictors of quality of life of patients with chronic obstructive pulmonary disease

Predictors of quality of life of patients with chronic obstructive pulmonary disease

Evaluation of multidimensional COPD-related subjective fatigue following a Pulmonary Rehabilitation programme

Characteristics and health related quality of life in a population with advanced chronic obstructive pulmonary disease, a cross-sectional study

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