A comprehensive framework for detecting economic growth expenses under ecological economics principles in China

Fang, Zhou; Wang, Huimin; Xue, Shi; Zhang, Fan; Wang, Yixin; Yang, Shiliang; Zhou, Qin; Cheng, Changgao; Zhong, Yuchun; Yang, Yang; Liu, Gang; Chen, Junyu; Qiu, Lei; Zhi, Yanling

doi:10.1016/j.horiz.2022.100035

Cited by 11 publications

(4 citation statements)

References 41 publications

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“…Finally, it is imperative to further update China's industrial structure. As the country has largely reached the late stage of industrialization, its industrial structure is set to shift from being industrial‐led to a new stage of structural upgrading (Z. Fang et al, 2022). To this end, businesses must be encouraged and assisted in transforming to sectors and goods that exhibit lower water use and greater water‐saving advantages.…”

Section: Discussionmentioning

confidence: 99%

Forecasting China's water use peak path under coordinating perspective from economic development and technological progress

Zhou

Zhang

et al. 2023

Natural Resources Forum

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China holds the distinction of being the foremost global consumer of water resources and contends with a significant level of water scarcity. In light of this quandary, China has been assiduously endeavoring to foster water conservation practices with the ultimate objective of reaching a peak point in water use. In this paper, we construct a framework for forecasting China's total water use (TWU) peak path. In this framework, we select influencing factors in terms of both economy and technology to forecast the peak path of China's TWU under six different scenarios, and analyze the economic and technological circumstances at the peak. Our findings indicate that China's TWU will persist in its upward trend based on both the high growth and business as usual scenarios. The projected peak period is estimated to transpire in 2037, 2032, 2030, and 2028, respectively, with the corresponding peak levels amounting to 644.03, 633.93, 625.79, and 620.92 billion m3. However, in the low growth scenarios, China's TWU reached its peak in 2013. The extent of economic development plays a pivotal role in determining the timing and manner of water usage peaking. Early peaking of water usage could potentially result in a loss of gross domestic product (GDP). Furthermore, technological advancements hold the potential to facilitate a reduction in water use without requiring a significant trade‐off between resource conservation and economic development. The results of sensitivity analysis show that the average acreage of water used for irrigation on cropland, GDP, water use efficiency, and population contribute the most to TWU, while the increase in the proportion of industrial, service, and water‐saving irrigation area can reduce water use. Our analytical framework provides a commonly applicable solution for the water use forecast in areas seeking to reach the water use peak or to achieve sustainable development.

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Section: Discussionmentioning

confidence: 99%

Forecasting China's water use peak path under coordinating perspective from economic development and technological progress

Zhou

Zhang

et al. 2023

Natural Resources Forum

Self Cite

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“…Zhang et al (2018) [34] investigated the EWP of 82 countries in 2012 and found that industrialized nations and G20 nations have relatively low EWP values. Fang et al [35] analyzed the changing trend of the EWP of 30 provinces in China from 2005 to 2010, using data from 30 provinces. Using exploratory spatial-data analysis, Xu et al [36] examined the spatiotemporal characteristics of the EWP across 30 Chinese provinces.…”

Section: Efficiency Measurement From Total Factorsmentioning

confidence: 99%

A Effectiveness-and Efficiency-Based Improved Approach for Measuring Ecological Well-Being Performance in China

et al. 2023

IJERPH

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Finding solutions to the challenges posed by China’s urbanization is an urgent, pressing global concern. An effective approach for evaluating the ecological well-being performance (EWP) is a guideline for improvement. Most previous studies have focused on the evaluation of EWP efficiency without considering the effectiveness of the EWP, which may mislead the practice of improving the EWP. This paper proposed a bi-dimensional effectiveness and efficiency perspective evaluation of the EWP for pursuing sustainable development goals. The Ecological Consumption Index and the Human Development Index are selected to evaluate indicators for the EWP. The entropy method, line-weighted method, and four-quadrant evaluation framework are used to disclose EWP effectiveness. A Super SBM model and the DEA moving split-windows analysis method are applied to calculate the EWP efficiency. Data from 30 provinces in China for the period of 1997 to 2019 have been collected for empirical study to demonstrate the effectiveness of the proposed method. The main findings of the case study are: (1) The ECI and HDI increased during the study period, while the annual average value of the EWP efficiency among 30 provinces in China has decreased with fluctuation; (2) provinces in southern China and Chongqing have a low level of ECI and demonstrate good performance in the HDI; and (3) most developed regions, such as Beijing, Shanghai, and Guangdong, have not presented the best EWPs. The results of this study can provide a basis for understanding the EWP in China so as to formulate targeted sustainable-development strategies.

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“…The privileged chemistry of cysteine has not only endowed this amino acid with a central role in protein function but over the last two decades has designated this residue as the preferred small molecule handle for covalent drug discovery [15][16][17][18][19][20][21] . With over 260,000 cysteines encoded in the human genome and many identified in disease-causing proteins, numerous chemical probes and medicines have been developed to target cysteines [22][23][24][25][26][27][28][29][30][31][32][33][34][35][36] . Taking advantage of the unique attributes of covalency has not only expanded the druggable genome but enabled the targeting of traditionally challenging protein classes including transcription factors and scaffolding proteins [37][38][39][40][41][42][43][44][45][46][47][48][49][50][51][52][53][54] .…”

Section: Introductionmentioning

confidence: 99%

Systematic Targeting of Protein Complexes with Molecular COUPLrs

Yang,

Harry,

Chong

et al. 2024

Preprint

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Molecular glues that engage protein complexes have transformed the study of cell biology and have had a direct impact on clinical oncology. However, the identification of new glue classes and their corresponding protein complexes has remained largely serendipitous. To overcome this challenge, we report the development of molecular COUPLrs, elaborated small molecules flanked by two cysteine-reactive warheads, as well as CONNECT, an integrated chemical proteomic platform for target deconvolution. By profiling a library of molecular COUPLrs across 13 cancer cell lines, we uncovered hundreds of proteins that can be coupled together, including in some cases in mutant selective fashions. We develop an advanced COUPLr for the oncogene EML4-ALK, which engages the fusion outside of its kinase domain, restricts protein dynamics, and disrupts EML4-ALK signaling. Collectively, molecular COUPLrs substantially expand the scope of proteins that can be chemically connected, providing an unbiased approach to identify small molecules that target protein complexes.

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A comprehensive framework for detecting economic growth expenses under ecological economics principles in China

Cited by 11 publications

References 41 publications

Forecasting China's water use peak path under coordinating perspective from economic development and technological progress

Forecasting China's water use peak path under coordinating perspective from economic development and technological progress

A Effectiveness-and Efficiency-Based Improved Approach for Measuring Ecological Well-Being Performance in China

Systematic Targeting of Protein Complexes with Molecular COUPLrs

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