A comprehensive finite element model for studying Cochlear-Vestibular interaction

Liang, Junfeng; Zhang, Ke; Welch, Paige V; Gan, Rong Z.; Dai, Chenkai

doi:10.1080/10255842.2021.1946522

Cited by 4 publications

(5 citation statements)

References 53 publications

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“…Mesh size convergence analysis was not conducted due to the already very fine average element size of approximately 0.2 mm. This size is sufficient when considering the larger element sizes utilized by previous models [41,42]. However, applying mesh size convergence analysis to future iterations of the model may reduce the processing power and time necessary for simulation [43].…”

Section: Meshingmentioning

confidence: 99%

“…The elastic modulus and β damping coefficient of the OWM were identical to the RWM; however, in this model, these properties were unimportant given that the OWM was assigned a set displacement for each trial. The material properties of the cupulae were assigned according to a prior computational model of the inner ear, which studied vestibulo-cochlear interaction [41]. The material properties of the maculae were assigned according to those reported by a model that isolated the maculae of the otolith organs and separated them into two distinct layers, as was performed in this study [34].…”

Section: Materials Propertiesmentioning

confidence: 99%

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Finite Element Modeling of Residual Hearing after Cochlear Implant Surgery in Chinchillas

et al. 2023

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Cochlear implant (CI) surgery is one of the most utilized treatments for severe hearing loss. However, the effects of a successful scala tympani insertion on the mechanics of hearing are not yet fully understood. This paper presents a finite element (FE) model of the chinchilla inner ear for studying the interrelationship between the mechanical function and the insertion angle of a CI electrode. This FE model includes a three-chambered cochlea and full vestibular system, accomplished using µ-MRI and µ-CT scanning technologies. This model’s first application found minimal loss of residual hearing due to insertion angle after CI surgery, and this indicates that it is a reliable and helpful tool for future applications in CI design, surgical planning, and stimuli setup.

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Section: Meshingmentioning

confidence: 99%

Section: Materials Propertiesmentioning

confidence: 99%

Finite Element Modeling of Residual Hearing after Cochlear Implant Surgery in Chinchillas

et al. 2023

Self Cite

View full text Add to dashboard Cite

show abstract

“…Mesh size convergence analysis was not conducted due to the already very fine average element size of about 0.2 mm. This size is sufficient when considering the larger element sizes utilized by previous models [33,34]. However, applying mesh size convergence analysis to future iterations of the model may reduce the processing power and time necessary for simulation [35].…”

Section: Meshingmentioning

confidence: 99%

Finite Element Modeling of Residual Hearing after Cochlear Implant Surgery in Chinchillas

Castle

Liang

Smith

et al. 2023

Preprint

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Cochlear implant (CI) surgery is one of the most utilized treatments for severe hearing loss. However, the effects of a successful scala tympani insertion on the mechanics of hearing are not yet fully understood. This paper presents a finite element (FE) model of the chinchilla inner ear for studying the interrelationship between the mechanical function and the insertion angle of a CI electrode. This FE model includes a three-chambered cochlea and full vestibular system, accomplished using μ-MRI and μ-CT scanning technology. This models first application found minimal loss of residual hearing due to insertion angle after CI surgery and indicates that it is a reliable and helpful tool for future application in CI design, surgical planning, and stimuli setup.

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“…To ascertain the ideal ramp slope for the new stimulation protocol, we employed a virtual model of the rhesus monkey ear to perform simulations. The model's specific characteristics were previously outlined in our studies [18][19][20]. Our model design adopted a methodology akin to cochlear implant stimulation models, comprising two primary components [20].…”

Section: Computational Modelingmentioning

confidence: 99%

A Virtual Inner Ear Model Selects Ramped Pulse Shapes for Vestibular Afferent Stimulation

Chen,

Sprigg,

Castle

et al. 2023

Bioengineering

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Bilateral vestibular deficiency (BVD) results in chronic dizziness, blurry vision when moving the head, and postural instability. Vestibular prostheses (VPs) show promise as a treatment, but the VP-restored vestibulo-ocular reflex (VOR) gain in human trials falls short of expectations. We hypothesize that the slope of the rising ramp in stimulation pulses plays an important role in the recruitment of vestibular afferent units. To test this hypothesis, we utilized customized programming to generate ramped pulses with different slopes, testing their efficacy in inducing electrically evoked compound action potentials (eCAPs) and current spread via bench tests and simulations in a virtual inner model created in this study. The results confirmed that the slope of the ramping pulses influenced the recruitment of vestibular afferent units. Subsequently, an optimized stimulation pulse train was identified using model simulations, exhibiting improved modulation of vestibular afferent activity. This optimized slope not only reduced the excitation spread within the semicircular canals (SCCs) but also expanded the neural dynamic range. While the model simulations exhibited promising results, in vitro and in vivo experiments are warranted to validate the findings of this study in future investigations.

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A comprehensive finite element model for studying Cochlear-Vestibular interaction

Cited by 4 publications

References 53 publications

Finite Element Modeling of Residual Hearing after Cochlear Implant Surgery in Chinchillas

Finite Element Modeling of Residual Hearing after Cochlear Implant Surgery in Chinchillas

Finite Element Modeling of Residual Hearing after Cochlear Implant Surgery in Chinchillas

A Virtual Inner Ear Model Selects Ramped Pulse Shapes for Vestibular Afferent Stimulation

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