A comprehensive evaluation of flexible FDM/FFF 3D printing filament as a potential material in medical application

Haryńska, Agnieszka; Carayon, Iga; Kosmela, Paulina; Szeliski, Kamil; Łapiński, Marcin; Pokrywczyńska, Marta; Kucińska-Lipka, Justyna; Janik, Helena

doi:10.1016/j.eurpolymj.2020.109958

Cited by 49 publications

(22 citation statements)

References 48 publications

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“…According to several authors, to improve the mechanical properties and reduce the anisotropy of the printed part, it is suggested to print with a raster angle of 45°/−45° [ 92 , 99 ]. Haryńska and coworkers [ 102 ] demonstrated that the tensile strength is higher for an angle of 45°/−45° compared to the raster angles of 0 and 90°. In addition, the authors explained that this happens because of the greater tension of the layers positioned perpendicularly to the stretching direction of the printed specimen [ 102 ].…”

Section: Processing Parameters In Ammentioning

confidence: 99%

“…Haryńska and coworkers [ 102 ] demonstrated that the tensile strength is higher for an angle of 45°/−45° compared to the raster angles of 0 and 90°. In addition, the authors explained that this happens because of the greater tension of the layers positioned perpendicularly to the stretching direction of the printed specimen [ 102 ].…”

Section: Processing Parameters In Ammentioning

confidence: 99%

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3D Printing of Polymeric Bioresorbable Stents: A Strategy to Improve Both Cellular Compatibility and Mechanical Properties

2022

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One of the leading causes of death is cardiovascular disease, and the most common cardiovascular disease is coronary artery disease. Percutaneous coronary intervention and vascular stents have emerged as a solution to treat coronary artery disease. Nowadays, several types of vascular stents share the same purpose: to reduce the percentage of restenosis, thrombosis, and neointimal hyperplasia and supply mechanical support to the blood vessels. Despite the numerous efforts to create an ideal stent, there is no coronary stent that simultaneously presents the appropriate cellular compatibility and mechanical properties to avoid stent collapse and failure. One of the emerging approaches to solve these problems is improving the mechanical performance of polymeric bioresorbable stents produced through additive manufacturing. Although there have been numerous studies in this field, normalized control parameters for 3D-printed polymeric vascular stents fabrication are absent. The present paper aims to present an overview of the current types of stents and the main polymeric materials used to fabricate the bioresorbable vascular stents. Furthermore, a detailed description of the printing parameters’ influence on the mechanical performance and degradation profile of polymeric bioresorbable stents is presented.

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Section: Processing Parameters In Ammentioning

confidence: 99%

Section: Processing Parameters In Ammentioning

confidence: 99%

3D Printing of Polymeric Bioresorbable Stents: A Strategy to Improve Both Cellular Compatibility and Mechanical Properties

2022

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“…The short-term degradation studies of the obtained filaments were performed in selected media: 2 M HCl, 5 M NaOH, and 0.1 M CoCl 2 in 20% H 2 O 2 . This is a standard procedure previously reported in the literature [31][32][33][34][35][36]. Filaments were cut into samples of 10 mm length and 3 mm diameter.…”

Section: Short Term Degradation Studies In Selected Mediamentioning

confidence: 99%

Composite Polyurethane-Polylactide (PUR/PLA) Flexible Filaments for 3D Fused Filament Fabrication (FFF) of Antibacterial Wound Dressings for Skin Regeneration

et al. 2021

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This paper addresses the potential application of flexible thermoplastic polyurethane (TPU) and poly(lactic acid) (PLA) compositions as a material for the production of antibacterial wound dressings using the Fused Filament Fabrication (FFF) 3D printing method. On the market, there are medical-grade polyurethane filaments available, but few of them have properties required for the fabrication of wound dressings, such as flexibility and antibacterial effects. Thus, research aimed at the production, characterization and modification of filaments based on different TPU/PLA compositions was conducted. The combination of mechanical (tensile, hardness), structural (FTIR), microscopic (optical and SEM), degradation (2 M HCl, 5 M NaOH, and 0.1 M CoCl2 in 20% H2O2) and printability analysis allowed us to select the most promising composition for further antibacterial modification (COMP-7,5PLA). The thermal stability of the chosen antibiotic—amikacin—was tested using processing temperature and HPLC. Two routes were used for the antibacterial modification of the selected filament—post-processing modification (AMI-1) and modification during processing (AMI-2). The antibacterial activity and amikacin release profiles were studied. The postprocessing modification method turned out to be superior and suitable for wound dressing fabrication due to its proven antimicrobial activity against E. coli, P. fluorescens, S. aureus and S. epidermidis bacteria.

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“…This paper aims to demonstrate an approach to manufacturing lightweight PLA foams by FDM 3D-printing technology, integrated with CFAs. Two parameters, printing temperature and flow rate, are assumed to be effective parameters that may influence material tailoring [ 27 , 28 ] and foam density through the size of bubbles produced during fabrication. Experiments are conducted to examine the effects of printing temperature and flow rate on the bubble size, micro-scale material connections, tensile stiffness and strength.…”

Section: Introductionmentioning

confidence: 99%

Porous PLAs with Controllable Density by FDM 3D Printing and Chemical Foaming Agent

2021

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This paper shows how fused decomposition modeling (FDM), as a three-dimensional (3D) printing technology, can engineer lightweight porous foams with controllable density. The tactic is based on the 3D printing of Poly Lactic Acid filaments with a chemical blowing agent, as well as experiments to explore how FDM parameters can control material density. Foam porosity is investigated in terms of fabrication parameters such as printing temperature and flow rate, which affect the size of bubbles produced during the layer-by-layer fabrication process. It is experimentally shown that printing temperature and flow rate have significant effects on the bubbles’ size, micro-scale material connections, stiffness and strength. An analytical equation is introduced to accurately simulate the experimental results on flow rate, density, and mechanical properties in terms of printing temperature. Due to the absence of a similar concept, mathematical model and results in the specialized literature, this paper is likely to advance the state-of-the-art lightweight foams with controllable porosity and density fabricated by FDM 3D printing technology.

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A comprehensive evaluation of flexible FDM/FFF 3D printing filament as a potential material in medical application

Cited by 49 publications

References 48 publications

3D Printing of Polymeric Bioresorbable Stents: A Strategy to Improve Both Cellular Compatibility and Mechanical Properties

3D Printing of Polymeric Bioresorbable Stents: A Strategy to Improve Both Cellular Compatibility and Mechanical Properties

Composite Polyurethane-Polylactide (PUR/PLA) Flexible Filaments for 3D Fused Filament Fabrication (FFF) of Antibacterial Wound Dressings for Skin Regeneration

Porous PLAs with Controllable Density by FDM 3D Printing and Chemical Foaming Agent

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