Abstract:A comprehensive mathematical model of cerebral hemodynamics, with separate regulation of multiple brain regions, is presented. The main sectors included in the model are: the Circle of Willis, the hemodynamic circulation in the six districts perfused by the cerebral arteries, venous return with collapsible veins, cerebrospinal fluid circulation, and intracranial elasticity. Furthermore, each cerebral district is independently regulated following changes in cerebral perfusion pressure and CO 2 tension. In this … Show more
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