A comprehensive assessment of human exposure to phthalates from environmental media and food in Tianjin, China

Ji, Yaqin; Wang, Fumei; Zhang, Leibo; Shan, Chunyan; Zhang, Bai; Sun, Zilin; Liu, Lingling; Shen, Boxiong

doi:10.1016/j.jhazmat.2014.06.055

Cited by 129 publications

(39 citation statements)

References 50 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Various phthalates (most commonly DEHP, DnBP, and DiBP) have been detected in food products such as milk, fat-enriched foods, meat, fish, seafood, beverages, grains, and vegetables [10]. Ji, et al [22] evaluated 448 samples including foodstuffs, ambient PM10, drinking water, soil, and indoor dust samples in China to determine the distribution of six priority phthalates. They highlighted that environmental factors might be related to exposure to phthalates as well as food preference.…”

Section: Discussionmentioning

confidence: 99%

Human Milk Phthalate Diester Levels in Turkey

Dinleyici¹

2018

Clinics Mother Child Health

View full text Add to dashboard Cite

Introduction: Newborn and infants are among the most susceptible age groups to endocrine disruption due to potential environmental toxins like phthalates. Differing results have been found on phthalate exposure through human milk from different geographic parts of the world. In this study, we aim to evaluate six different phthalate diesters in human milk samples. Methods: In this part of the Human Milk Artificial Pollutants (HUMAP) study, human milk samples were analyzed using GC-MS to indicate the presence of bis (2-ethylhexyl) phthalate (DEHP), benzyl butyl phthalate (BBP), dibutyl phthalate (DBP), di-"isononyl" phthalate (DINP), di-"isodecyl" phthalate (DIDP), and din -octyl phthalate (DNOP). Results: This study included 72 mothers aged 18 to 41 years; human milk samples were taken from the mothers who gave their consent to participate within 7 to 79 days after birth (mean 34 ± 20 days). We did not detected phthalate esters as DEHP, BBP, DBP, DINP, DIDP, and DNOP in 72 human milk samples. Discussion: In this study, we did not find phthalate diesters in human milk samples in Turkey. Different results of previous studies about human milk phthalate levels might be related to geography, maternal factors, or analytical methods. In conclusion, potential further studies should continue for potential chemical contamination of human milk.

show abstract

Section: Discussionmentioning

confidence: 99%

Human Milk Phthalate Diester Levels in Turkey

Dinleyici¹

2018

Clinics Mother Child Health

View full text Add to dashboard Cite

show abstract

“…Since they are not covalently bound to plastics, phthalates can be released into the environment and have been widely detected in China [e.g., air (Wang et al, 2016), soils (Ma et al, 2015), drinking water and edible food commodities (Ji et al, 2014)]. Humans may be exposed to these chemicals via ingestion, inhalation, and dermal absorption (Wittassek et al, 2011).…”

Section: Introductionmentioning

confidence: 99%

Associations of urinary 5-methyl-2′-deoxycytidine and 5-hydroxymethyl-2′-deoxycytidine with phthalate exposure and semen quality in 562 Chinese adult men

Pan

Jing

Yeung

et al. 2016

Environment International

View full text Add to dashboard Cite

“…Phthalates are alkyl diesters of phthalic acid and are used as plasticizers in PVC products, as solvents and fixatives in personal care products, children's toys and as additives in the enteric coating of some drug tablets. Since these compounds are not covalently bound to the products, they easily leach from them, leading to high human exposure ( Figure 3) (Ji et al, 2014). Phthalate exposure has been estimated by biomonitoring studies, and ranges between 1 and 2 μg/kg bw/d of a single compound for adults and up to 4 μg/kg bw/d for children (Bergh, Torgrip, Emenius, & Ostman, 2011;Fromme et al, 2004).…”

Section: Bpa and Phthalatesmentioning

confidence: 99%

How microplastic components influence the immune system and impact on children health: Focus on cancer

Segovia-Mendoza

Nava-Castro

Palacios-Arreola

et al. 2020

Birth Defects Research

View full text Add to dashboard Cite

Background: As a result of human socioeconomic activity, industrial wastes have increased distressingly. Plastic pollution is globally distributed across the world due to its properties of buoyancy and durability. A big health hazard is the sorption of toxicants to plastic while traveling through the environment. Two broad classes of plastic-related chemicals are of critical concern for human health-bisphenols and phthalates. Bisphenol A (BPA) is an endocrine-disruptor compound (EDC) with estrogenic activity. It is used in the production of materials that are used daily. The endocrine modulating activity of BPA and its effects on reproductive health has been widely studied. BPA also has effects on the immune system; however, they are poorly investigated and the available data are inconclusive. Phthalates are also EDCs used as plasticizers in a wide array of daily-use products. Since these compounds are not covalently bound to the plastic matrix, they easily leach out from it, leading to high human exposure. These compounds exert several cell effects through modulating different endocrine pathways, such as estrogen, androgen, peroxisome proliferator-activated receptor gamma, and arylhydrocarbon receptor pathways. The exposure to both classes of plastic derivatives during critical periods has detrimental effects on human health. Methods: In this review, we have compiled the most important of their perinatal effects on the function of the immune system and their relationship to the development of different types of cancer. Results/Conclusion: The administration of bisphenols and phthalates during critical stages of development affects important immune system components, and the immune function; which might be related to the development of different diseases including cancer.

show abstract

A comprehensive assessment of human exposure to phthalates from environmental media and food in Tianjin, China

Cited by 129 publications

References 50 publications

Human Milk Phthalate Diester Levels in Turkey

Human Milk Phthalate Diester Levels in Turkey

Associations of urinary 5-methyl-2′-deoxycytidine and 5-hydroxymethyl-2′-deoxycytidine with phthalate exposure and semen quality in 562 Chinese adult men

How microplastic components influence the immune system and impact on children health: Focus on cancer

Contact Info

Product

Resources

About