A comparison of the rate of recovery of in exhaled breath with 2H in body water following ingestion of [2H/13C]octanoic acid in a dog

Comparison of the carbon 13-labeled octanoic acid breath test and ultrasonography for assessment of gastric emptying of a semisolid meal in dogs

“…Results of our study further substantiate these findings because the mean difference between t ½ (BT) and t 50% (GEU) was 1.55 hours, similar to the 1.33 hours previously reported for the difference between gastric half-emptying time of the 13 C-OBT and a real-time measure of gastric emptying (the deuterium-labeledoctanoic acid saliva test) in dogs. 32 The application of a correction factor to account for the postgastric processing of 13 C-octanoic acid in dogs or, indeed, whether such a factor is appropriate requires further analysis.…”

Oral and intravenous l‐[1‐13C]phenylalanine delivery measure similar rates of elimination when gastric emptying and splanchnic extraction are accounted for in adult mixed hounds1–4

“…These values are consistent with previous literature values. Gastric emptying half‐times estimated by scintigraphy ranged from 45 to 294 min in fasted dogs fed a single daily test meal (Wyse et al., 2003). In humans consuming solid meals, gastric emptying half‐times have been reported to range from 20 to 117 min (Siegel et al., 1988; Maes et al., 1994; Bromer et al., 2002; Woerle et al., 2008), while those consuming liquid meals have reported half‐times ranging between 14 and 110 min (Clements et al., 1978).…”