A comparison of the effects on bispectral index of mild vs. moderate hypothermia during cardiopulmonary bypass

Honan, D.; Doherty, Dermot; Frizelle, Henry P.

doi:10.1017/s0265021505002309

Cited by 21 publications

(18 citation statements)

References 22 publications

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“…Similarly, Bauer et al 34 found a 30% reduction in propofol infusion rates and plasma propofol concentration in their BIS-guided group during on-pump coronary artery bypass surgery. [38][39][40] However, the results of the logistic regression analysis confirm that the reduction of noradrenaline requirements correlates most strongly with the reduction in the SPC, which results from BISguided administration of sevoflurane. As the target range of BIS values was set to 40 to 60, the concentration of sevoflurane in the oxygenator fresh gas supply was not reduced when BIS values exceeded 40 and was never reduced below 0.3%.…”

Section: Discussionmentioning

confidence: 82%

Bispectral index guided titration of sevoflurane in on-pump cardiac surgery reduces plasma sevoflurane concentration and vasopressor requirements

Nitzschke

Wilgusch

Kersten

et al. 2014

European Journal of Anaesthesiology

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Section: Discussionmentioning

confidence: 82%

Bispectral index guided titration of sevoflurane in on-pump cardiac surgery reduces plasma sevoflurane concentration and vasopressor requirements

Nitzschke

Wilgusch

Kersten

et al. 2014

European Journal of Anaesthesiology

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“…However, hypothermia during CPB has also been reported to decrease BIS values [9]; thus, the interpretation of the BIS values in the current study might require further attention. The body temperatures of the patients were kept at 35.1℃ and 35.3℃ during partial CPB, and this mild hypothermia may have caused the decreased BIS values.…”

Section: Discussionmentioning

confidence: 85%

Cross-clamping of the descending thoracic aorta leads to the asymmetrical distribution of propofol during cardiopulmonary bypass surgery

Yamauchi-Satomoto

Adachi

Kurita

et al. 2012

Korean J Anesthesiol

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BackgroundWe hypothesized that cross-clamping of the descending thoracic aorta (CcDTA) would result in significant changes in plasma propofol concentrations (Cp) proximal and distal to the cross-clamp. We investigated the effect of CcDTA on Cp centrally and distally, including the pulmonary artery and the cardiopulmonary bypass (CPB) cannula.MethodsThe bispectral index (BIS) was recorded during CcDTA in eight patients undergoing thoracic aortic surgery using target-controlled total intravenous anesthesia with propofol. The calculated Cp was maintained at 3 µg/ml. Cp was measured in blood samples drawn from the right radial artery, left dorsalis pedis artery, pulmonary artery, and the long venous CPB cannula.ResultsComplete data were obtained from six patients. BIS decreased significantly in all cases 5 minutes after initiating CcDTA. BIS continued to decrease in association with increasing propofol concentrations. During CcDTA, Cp in samples from the radial and pulmonary arteries (3.5 ± 0.50 and 2.9 ± 0.63 µg/ml, mean ± SD) was significantly higher than in samples from the dorsalis pedis artery and the venous cannula (1.1 ± 0.22 and 1.4 ± 0.02 µg/ml) (P < 0.05).ConclusionsThe results suggest that almost all of the blood returning from the superior vena cava during CcDTA directly enters the pulmonary circulation without mixing with blood from the inferior vena cava. Observed changes in anesthetic blood concentrations could be due to the presence of a split circulation and asymmetrical distribution of propofol induced by CcDTA and CPB.

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“…The Narcotrend monitor has some advantages. It has two channels: one is used for EEG monitoring during general anesthesia, and the other to compare the statuses of two hemispheres [17][18][19][20] . Anesthesia depth monitoring with the Narcotrend monitor has no infl uence on the heart surgery in the presence of CPB, but BIS may affect the CPB.…”

Section: Discussionmentioning

confidence: 99%

Aplicação do monitor Narcotrend® para avaliar a profundidade da anestesia em crianças submetidas à cirurgia cardíaca: estudo prospectivo e controlado

Jiang

Qiao

et al. 2013

Rev. Bras. Anestesiol.

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Background and objectives: To investigate the clinic effectiveness, safety and feasibility of Narcotrend® monitor for evaluation of depth of anesthesia in congenital heart disease (CHD) infants undergoing cardiac surgery. Methods: A total of 80 infants receiving general anesthesia in selective surgery were randomly selected. Infants were assigned into two groups (n = 40 per group). In the Narcotrend group, the depth of anesthesia was monitored with the Narcotrend monitor. In the standard group, the depth of anesthesia was controlled according to the experience. The mean arterial pressure (MAP) and heart rate (HR) were determined, as well as the dose of fentanyl, muscle relaxant, recovery time and extubation time were recorded. Results: In both groups, vital signs were stable during the surgery. When compared with the standard group, the MAP and HR were more stable, the total dose of fentanyl and muscle relaxant were signifi cantly reduced and the recovery time and extubation time were markedly shortened in the Narcotrend group. Conclusion: The application of Narcotrend monitor was benefi cial to the control of the depth of anesthesia in CHD infants receiving total intravenous anesthesia, in which small amount of narcotics can achieve optimal anesthesia. Moreover, the recovery time and extubation time are reduced and the harmful consequence such as intraoperative awareness can be avoided.

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A comparison of the effects on bispectral index of mild vs. moderate hypothermia during cardiopulmonary bypass

Cited by 21 publications

References 22 publications

Bispectral index guided titration of sevoflurane in on-pump cardiac surgery reduces plasma sevoflurane concentration and vasopressor requirements

Bispectral index guided titration of sevoflurane in on-pump cardiac surgery reduces plasma sevoflurane concentration and vasopressor requirements

Cross-clamping of the descending thoracic aorta leads to the asymmetrical distribution of propofol during cardiopulmonary bypass surgery

Aplicação do monitor Narcotrend® para avaliar a profundidade da anestesia em crianças submetidas à cirurgia cardíaca: estudo prospectivo e controlado

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