A comparison of surgical devices for grade II and III hemorrhoidal disease. Results from the LigaLongo Trial comparing transanal Doppler-guided hemorrhoidal artery ligation with mucopexy and circular stapled hemorrhoidopexy

Venara, Aurélien; Podevin, J.; Godeberge, Philippe; Redon, Y.; Barussaud, Marie-Line; Sielezneff, I.; Queralto, M.; Bourbao, Cecile; Chiffoleau, Anne; Lehur, P.‐A.

doi:10.1007/s00384-018-3093-8

Cited by 12 publications

(6 citation statements)

References 14 publications

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“…In the longer term, recurrence of symptoms is not uncommon. Most recent evidence suggests that open haemorrhoidectomy is the most painful in the short term, but it is the least expensive, and better quality of life is observed in the long-term [4][5][6]. At present, all three interventions are recommended for use [3].…”

Section: Introductionmentioning

confidence: 99%

Protocol for the ORION trial (RadiO fRequency ablatION for haemorrhoids): a randomised controlled trial

et al. 2022

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Background Haemorrhoids are common and can significantly impact the personal and working lives of individuals. Those with more severe symptoms and those not responding to conservative management may require surgery. Current surgical techniques are associated with a degree of postoperative discomfort which may delay return to normal activity. Recurrence is lower in more radical procedures but resulting pain is higher. Radiofrequency ablation (RFA) is a new technique that is gaining popularity and has several hypothesised benefits, including reduced pain and recurrence. However, available evidence is limited. A recent overview from the National Institute for Health and Clinical Excellence recommended more research, in the form of randomised controlled trials, be carried out before further investment is made by national health services. Our aim is to assess whether RFA is at least as good in terms of recurrence as existing surgical interventions, but superior in terms of pain, for patients with symptomatic grade II and III haemorrhoids. Methods The RadiO fRequency ablatION for haemorrhoids (ORION) trial will be a pragmatic multicentre patient/assessor-blind parallel group-controlled trial with economic evaluation. The target sample size is 376 participants (188 per arm) and is based on two co-primary endpoints: (i) a non-inferiority design for recurrence and (ii) superiority design for pain at seven days. Participants with grade II or III haemorrhoids will be recruited in 16 National Health Service hospitals and randomised (1:1) to either RFA or surgeon’s choice of surgery. Conclusions Results will inform future practice for the treatment of grade II–III haemorrhoids and provide evidence for national health services on future investments in RFA. Trial registration ISRCTN14474552.

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Section: Introductionmentioning

confidence: 99%

Protocol for the ORION trial (RadiO fRequency ablatION for haemorrhoids): a randomised controlled trial

et al. 2022

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“…Surgical intervention HAL-RAR (hemorrhoidal artery ligation, recto-anal repair) as an effective method of minimally invasive treatment is an alternative to traditional hemorrhoidectomy for the treatment of hemorrhoidal disease (haemorrhoidaldesease -HD) for 2 [10,14] and even 3 and 4 stages of the disease [1,2,3]. In most cases it combines low trauma and a comfortable postoperative period for the patient, as well as ease of implementation for the surgeon [1,4].…”

Section: Introductionmentioning

confidence: 99%

Originalsubmucosalsuture in Thetreatment of Gradeiv Hemorrhoids During Mucopexy: Clinical Results and Postoperative Pain Syndrome

Костенко¹,

Масленников²,

Ясенявская³

2021

ArveMED

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In a comparative clinical study the effect of the method of desarterization with mucopexy in the minimally invasive treatment forgrade 4 hemorrhoidaldisease on the postoperative period was studied. The authors proposed an original patented submucosal suture with a minimal tissue trauma. It enables to achieve radical desarterization while preserving the anatomical structures of the surgical anal canal. A statistically significant decrease in pain syndrome in the postoperative period was shown in comparison with the use of a conventional twisted suture, as well as a decrease in recurrence of prolapse and bleeding.

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“…Una técnica que ha surgido en el último tiempo para el tratamiento de este tipo de pacientes y que ha sido comparada en la cirugía propuesta por Longo es la desarterialización hemorroidal transanal guiada por Doppler, primero descripta por Morinaga et al 13 Algunos estudios han demostrado que esta última técnica está asociada a menor dolor postoperatorio y menos complicaciones graves, 14,15 sin embargo, otros no han encontrado diferencias entre uno y otro método. 14 Creemos que todavía faltan estudios para poder determinar la superioridad de una u otra técnica.…”

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Hemorroidopexia con sutura mecánica. Indicaciones en el 2021

Piccinini

Avellaneda

Carrie

2021

Rev. Argent. Coloproctol.

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A comparison of surgical devices for grade II and III hemorrhoidal disease. Results from the LigaLongo Trial comparing transanal Doppler-guided hemorrhoidal artery ligation with mucopexy and circular stapled hemorrhoidopexy

Abstract: clinicaltrials.gov -Identifier NCT01240772.

Cited by 12 publications

References 14 publications

Protocol for the ORION trial (RadiO fRequency ablatION for haemorrhoids): a randomised controlled trial

Protocol for the ORION trial (RadiO fRequency ablatION for haemorrhoids): a randomised controlled trial

Originalsubmucosalsuture in Thetreatment of Gradeiv Hemorrhoids During Mucopexy: Clinical Results and Postoperative Pain Syndrome

Hemorroidopexia con sutura mecánica. Indicaciones en el 2021

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