A Comparison of Microwave Ablation and Cryoablation for the Treatment of Renal Cell Carcinoma: A Systematic Literature Review and Meta-analysis

McClure, Timothy; Lansing, Austin; Ferko, Nicole; Wright, Gavin; Ghosh, Sudip Kumar; Raza, Sajjad; Kalsekar, Iftekhar; Clarke, K.; Talenfeld, Adam D.

doi:10.1016/j.urology.2023.06.001

Cited by 2 publications

(1 citation statement)

References 34 publications

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“…This short-term lower recurrence rate is probably attributed to the higher intertumoral temperature and larger ablation zone achieved with MWA. Regarding other outcomes, such as overall survival, disease-free survival, overall/major complications, procedure/ablation time, 1-to 3-month primary technique efficacy, and technical success, the authors reported no significant differences between MWA and other techniques [77].…”

Section: Recurrence Rates Following Ablative Techniquesmentioning

confidence: 93%

Ablative Treatments for Small Renal Masses and Management of Recurrences: A Comprehensive Review

Aveta,

Iossa,

Spena

et al. 2024

Life

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This review focuses on ablative techniques for small renal masses (SRMs), including radiofrequency ablation (RFA), cryoablation (CA), microwave ablation (MWA), and irreversible electroporation (IRE), and discusses recurrence management. Through an extensive literature review, we outline the procedures, outcomes, and follow-up strategies associated with each ablative method. The review provides a detailed examination of these techniques—RFA, CA, MWA, and IRE—elucidating their respective outcomes. Recurrence rates vary among them, with RFA and CA showing comparable rates, MWA demonstrating favorable short-term results, and IRE exhibiting promise in experimental stages. For managing recurrences, various strategies are considered, including active surveillance, re-ablation, or salvage surgery. Surveillance is preferred post-RFA and post-CA, due to slow SRM growth, while re-ablation, particularly with RFA and CA, is deemed feasible without additional complications. Salvage surgery emerges as a viable option for larger or resistant tumors. While ablative techniques offer short-term results comparable to surgery, further research is essential to understand their long-term effects fully. Decisions concerning recurrence management should consider individual and tumor-specific factors. Imaging, notably contrast-enhanced ultrasounds, plays a pivotal role in assessing treatment success, emphasizing the necessity of a multidisciplinary approach for optimal outcomes. The lack of randomized trials highlights the need for further research.

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Section: Recurrence Rates Following Ablative Techniquesmentioning

confidence: 93%

Ablative Treatments for Small Renal Masses and Management of Recurrences: A Comprehensive Review

Aveta,

Iossa,

Spena

et al. 2024

Life

View full text Add to dashboard Cite

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Percutaneous microwave ablation of T1a renal cell carcinomas: A 10‐year single‐center retrospective review

McCloskey,

Jacques,

McCloskey

et al. 2024

J Med Imag Rad Onc

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IntroductionPartial nephrectomy is currently the preferred treatment option for T1a renal cell carcinomas (RCC), with nephron‐sparing techniques, including microwave ablation, becoming more common in select patients. Primary aims are to document outcomes of microwave ablation for T1a RCCs in an Australian tertiary centre to add to the evidence for its safety and efficacy.MethodsThe prospectively maintained Sir Charles Gairdner Hospital Interventional Radiology database was retrospectively searched for all Renal Microwave ablations completed between June 2012 and February 2022. This database and a combination of hospital programmes including Agfa Impax PACS, Bossnet digital medical record and iSoft Clinical Manager were used to extract the relevant data which was anonymized and entered into an Excel spreadsheet for analysis.ResultsForty‐eight patients underwent microwave ablation for 50 tumours. Of these, there were two local and two distant recurrences. A fifth patient had metastases on presentation. Higher local recurrence rates were associated with larger tumour size (P = 0.043). Tumour proximity to the collecting system <4 mm was associated with higher rates of complications (P = 0.020). RENAL scores did not show statistically significant correlation with complications (P = 0.092) or local or distant recurrence. Notably, the study follow‐up time was longer than many comparative studies (mean = 2796, ~7.66 years censoring for death and mean = 832 days, ~2.28 years not censoring for death).ConclusionConsistent with the literature, this study further demonstrates that microwave ablation is a safe and efficacious option for treatment of T1a RCC.

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A Comparison of Microwave Ablation and Cryoablation for the Treatment of Renal Cell Carcinoma: A Systematic Literature Review and Meta-analysis

Cited by 2 publications

References 34 publications

Ablative Treatments for Small Renal Masses and Management of Recurrences: A Comprehensive Review

Ablative Treatments for Small Renal Masses and Management of Recurrences: A Comprehensive Review

Percutaneous microwave ablation of T1a renal cell carcinomas: A 10‐year single‐center retrospective review

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