A comparison of methods to detect low levels of Salmonella enterica in surface waters to support antimicrobial resistance surveillance efforts performed in multiple laboratories

Kraft, Autumn L.; Wells, Jim E.; Frye, Jonathan G.; Ibekwe, Abasiofiok M.; Durso, Lisa M.; Hiott, Lari; East, Cheryl; McConn, Betty R.; Franklin, Alison M.; Boczek, Laura A.; Garland, Jay L.; Kabera, Claudine; McDermott, Patrick F.; Ottesen, Andrea R.; Zheng, Jie; Cook, Kimberly L.; Sharma, Manan

doi:10.1016/j.scitotenv.2023.167189

Cited by 3 publications

(1 citation statement)

References 22 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Antibiotics are critical for the treatment of invasive ST infections [9]. However, the emergence of multidrug-resistant ST makes these infections more di cult to treat [10][11][12]. Meanwhile, antibiotic treatment resulted in a disruption of the gut microbiota, which were demonstrated to preclude ST infection by conferring colonization resistance, further increases susceptibility to ST infection [13].…”

Section: Introductionmentioning

confidence: 99%

Antimicrobial peptide AP2 ameliorates Salmonella Typhimurium infection by modulating gut microbiota

Li,

Fu,

et al. 2024

Preprint

View full text Add to dashboard Cite

Endogenous antimicrobial peptides/proteins contribute to reshape a healthy gut microbiota which play benefit roles in anti-inflammation and pathogen colonization resistance. Salmonella infection is one of the most frequently reported bacterial diseases worldwide. Manipulation of the gut microbiota through exogenous antimicrobial peptide may protects against Salmonella enterica colonization and improve clinical outcomes. In this study, results showed that oral administration of antimicrobial peptide AP2, an optimized version of native apidaecin IB (AP IB) had a protective effect against ST infections in mice indicated by alleviated ST-induced body weight loss and reduced the serum inflammatory cytokines. 16S rRNA-based analysis of microbiota from the cecum content showed that AP2 altered gut microbiota by significantly increasing the proportion of Bifidobacterium and decreasing Akkermansia at the genus level. Furthermore, the transplantation of fecal microbiota from AP2-treated donor mice, instead of control mice, significantly reduced caecal damage caused by ST. In conclusion, these findings hightlighted one of novel action mechanisms of exogenous antimicrobial peptide on ameliorating Salmonella Typhimurium infection by modulating gut microbiota.

show abstract

Section: Introductionmentioning

confidence: 99%

Antimicrobial peptide AP2 ameliorates Salmonella Typhimurium infection by modulating gut microbiota

Li,

Fu,

et al. 2024

Preprint

View full text Add to dashboard Cite

show abstract

An analysis of culture-based methods used for the detection and isolation of Salmonella spp., Escherichia coli, and Enterococcus spp. from surface water: A systematic review

McConn,

Kraft,

Durso

et al. 2024

Science of The Total Environment

View full text Add to dashboard Cite

A one health approach for monitoring antimicrobial resistance: developing a national freshwater pilot effort

Franklin,

Weller,

Durso

et al. 2024

Front. Water

Self Cite

View full text Add to dashboard Cite

Antimicrobial resistance (AMR) is a world-wide public health threat that is projected to lead to 10 million annual deaths globally by 2050. The AMR public health issue has led to the development of action plans to combat AMR, including improved antimicrobial stewardship, development of new antimicrobials, and advanced monitoring. The National Antimicrobial Resistance Monitoring System (NARMS) led by the United States (U.S) Food and Drug Administration along with the U.S. Centers for Disease Control and U.S. Department of Agriculture has monitored antimicrobial resistant bacteria in retail meats, humans, and food animals since the mid 1990’s. NARMS is currently exploring an integrated One Health monitoring model recognizing that human, animal, plant, and environmental systems are linked to public health. Since 2020, the U.S. Environmental Protection Agency has led an interagency NARMS environmental working group (EWG) to implement a surface water AMR monitoring program (SWAM) at watershed and national scales. The NARMS EWG divided the development of the environmental monitoring effort into five areas: (i) defining objectives and questions, (ii) designing study/sampling design, (iii) selecting AMR indicators, (iv) establishing analytical methods, and (v) developing data management/analytics/metadata plans. For each of these areas, the consensus among the scientific community and literature was reviewed and carefully considered prior to the development of this environmental monitoring program. The data produced from the SWAM effort will help develop robust surface water monitoring programs with the goal of assessing public health risks associated with AMR pathogens in surface water (e.g., recreational water exposures), provide a comprehensive picture of how resistant strains are related spatially and temporally within a watershed, and help assess how anthropogenic drivers and intervention strategies impact the transmission of AMR within human, animal, and environmental systems.

show abstract

A comparison of methods to detect low levels of Salmonella enterica in surface waters to support antimicrobial resistance surveillance efforts performed in multiple laboratories

Cited by 3 publications

References 22 publications

Antimicrobial peptide AP2 ameliorates Salmonella Typhimurium infection by modulating gut microbiota

Antimicrobial peptide AP2 ameliorates Salmonella Typhimurium infection by modulating gut microbiota

An analysis of culture-based methods used for the detection and isolation of Salmonella spp., Escherichia coli, and Enterococcus spp. from surface water: A systematic review

A one health approach for monitoring antimicrobial resistance: developing a national freshwater pilot effort

Contact Info

Product

Resources

About