A Comparison of Hydroxyapatite-Coated, Titanium-Coated, and Uncoated Tapered External-Fixation Pins. An in Vivo Study in Sheep*

Moroni, Antonio; Maltarello, Maria Cristina; Orienti, L.; Stea, Susanna; Giannini, Sandro

doi:10.2106/00004623-199804000-00011

Cited by 111 publications

(63 citation statements)

References 12 publications

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“…Earlier experimental studies have demonstrated a significant improvement on the purchase of loaded external fixation pins resulting from HA coating [2, 18,20]. In an experimental study on dogs, however, coating of unloaded pedicle screws with plasma-sprayed HA gave no improvement of the pull-out resistance of the screws after 6 weeks [29].…”

Section: Discussionmentioning

confidence: 95%

Hydroxyapatite coating enhances fixation of loaded pedicle screws: a mechanical in vivo study in sheep

2001

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Section: Discussionmentioning

confidence: 95%

Hydroxyapatite coating enhances fixation of loaded pedicle screws: a mechanical in vivo study in sheep

2001

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“…The test samples had a maximum score of 6. We then computed the rate of contact between bone and screw, on the assumption that the part in which it is possible to confirm the shape of a screw thread in the tissue specimen is the part contacted, based on a modification of the method reported by Giavaresi et al and Moroni et al 29,30 We did the actual image processing of the hematoxylin and eosin staining sample automatically using an optical microscope (BX51-33, Olympus Optical Co, Tokyo, Japan) connected to public domain image analysis software (Image J) and computed the data. In addition, the shape of the bone for the part corresponding to a screw thread was evaluated by Gram staining.…”

Section: Evaluation Of Bactericidal Effectmentioning

confidence: 99%

Clinical and histomorphometrical study on titanium dioxide-coated external fixation pins

Koseki¹,

Asahara²,

Shida³

et al. 2013

IJN

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Background:Pin site infection is the most common and significant complication of external fixation. In this work, the efficacy of pins coated with titanium dioxide (TiO 2 ) for inhibition of infection was compared with that of stainless steel control pins in an in vivo study. Methods: Pins contaminated with an identifiable Staphylococcus aureus strain were inserted into femoral bone in a rat model and exposed to ultraviolet A light for 30 minutes. On day 14, the animals were sacrificed and the bone and soft tissue around the pin were retrieved. The clinical findings and histological findings were evaluated in 60 samples. Results: Clinical signs of infection were present in 76.7% of untreated pins, but in only 36.7% of TiO 2 -coated pins. The histological bone infection score and planimetric rate of occupation for bacterial colonies and neutrophils in the TiO 2 -coated pin group were lower than those in the control group. The bone-implant contact ratio of the TiO 2 -coated pin group was significantly higher (71.4%) than in the control pin group (58.2%). The TiO 2 was successful in decreasing infection both clinically and histomorphometrically. Conclusion:The photocatalytic bactericidal effect of TiO 2 is thought to be useful for inhibiting pin site infection after external fixation.

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“…1,2 In order to improve the osteointegration between titanium implants and bone, surface modifications such as grit blasting of the metallic implant surface and coating with bioactive ceramic materials were explored. [3][4][5][6][7][8][9][10][11][12][13][14][15] Several studies on grit-blasted implants have shown that they lead to a higher percentage of bone contact and a higher removal torque when compared to the polished surface. [3][4][5][6] However, grit blasting may lead to a decrease in the fatigue strength and leave metallurgical point defects in the metal matrix.…”

Section: Introductionmentioning

confidence: 99%

Hydroxyapatite‐based composite for dental implants: An in vivo removal torque experiment

Kong

Kim

et al. 2002

J. Biomed. Mater. Res.

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Screw-shaped dental implants were fabricated from commercially pure Ti (c.p. Ti) and HA-based composites. The HA-based composites were fabricated by mixing HA with Al(2)O(3)-coated ZrO(2) powders. The mechanical properties of these composites were enhanced by a factor of 3. These were implanted into the rabbit tibiae and the removal torque to loosen the implants in vivo was measured in order to investigate the osteointegration. After a healing period of 6 weeks, the implants were retrieved with a torque gauge instrument. The HA-based composite implants showed an almost 2-times-higher removal torque when compared to the Ti implants (ANOVA, p < 0.05), indicating excellent biocompatibility to bone. Thus, HA-based composites had not only better mechanical properties but also similar bioactivity as HA itself. It is believed that a HA-based composite is suitable for artificial dental implants.

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A Comparison of Hydroxyapatite-Coated, Titanium-Coated, and Uncoated Tapered External-Fixation Pins. An in Vivo Study in Sheep*

Cited by 111 publications

References 12 publications

Hydroxyapatite coating enhances fixation of loaded pedicle screws: a mechanical in vivo study in sheep

Hydroxyapatite coating enhances fixation of loaded pedicle screws: a mechanical in vivo study in sheep

Clinical and histomorphometrical study on titanium dioxide-coated external fixation pins

Hydroxyapatite‐based composite for dental implants: An in vivo removal torque experiment

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