A comparison of HFrEF vs HFpEF's clinical workload and cost in the first year following hospitalization and enrollment in a disease management program

Murphy, T; Waterhouse, D; James, Stephanie; Casey, C.; Fitzgerald, E; O’Connell, Eoin; Watson, Chris; Gallagher, Joe; Ledwidge, Mark; McDonald, Ken

doi:10.1016/j.ijcard.2016.12.057

Cited by 25 publications

(18 citation statements)

References 18 publications

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“…Eleven articles had a prevalent and two an incident epidemiological approach. Three studies provided both types of results [ 25 – 27 ]. Twelve studies adopted the perspective of a third-party payer and six articles were categorized as a prospective study.…”

Section: Resultsmentioning

confidence: 99%

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Cost-of-illness studies in heart failure: a systematic review 2004–2016

Lesyuk

Kriza

Kolominsky-Rabas

2018

BMC Cardiovasc Disord

325

305

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BackgroundHeart failure is a major and growing medical and economic problem worldwide as 1–2% of the healthcare budget are spent for heart failure. The prevalence of heart failure has increased over the past decades and it is expected that there will be further raise due to the higher proportion of elderly in the western societies. In this context cost-of-illness studies can significantly contribute to a better understanding of the drivers and problems which lead to the increasing costs in heart failure.The aim of this study was to perform a systematic review of published cost-of-illness studies related to heart failure to highlight the increasing cost impact of heart failure.MethodsA systematic review was conducted from 2004 to 2016 to identify cost-of-illness studies related to heart failure, searching PubMed (Medline), Cochrane, Science Direct (Embase), Scopus and CRD York Database.ResultsOf the total of 16 studies identified, 11 studies reported prevalence-based estimates, 2 studies focused on incidence-based data and 3 articles presented both types of cost data. A large variation concerning cost components and estimates can be noted. Only three studies estimated indirect costs. Most of the included studies have shown that the costs for hospital admission are the most expensive cost element. Estimates for annual prevalence-based costs for heart failure patients range from $868 for South Korea to $25,532 for Germany. The lifetime costs for heart failure patients have been estimated to $126.819 per patient.ConclusionsOur review highlights the considerable and growing economic burden of heart failure on the health care systems. The cost-of-illness studies included in this review show large variations in methodology used and the cost results vary consequently. High quality data from cost-of-illness studies with a robust methodology applied can inform policy makers about the major cost drivers of heart failure and can be used as the basis of further economic evaluations.Electronic supplementary materialThe online version of this article (10.1186/s12872-018-0815-3) contains supplementary material, which is available to authorized users.

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Section: Resultsmentioning

confidence: 99%

“…To identify HF patients, the studies used different methods. Six articles referred to the ICD-10 (International Classification of Diseases), [ 27 – 32 ], five to the ICD-9 [ 24 , 26 , 33 – 35 ] and five [ 23 , 25 , 36 – 38 ] didn’t specify the ICD classification.…”

Section: Resultsmentioning

confidence: 99%

Cost-of-illness studies in heart failure: a systematic review 2004–2016

Lesyuk

Kriza

Kolominsky-Rabas

2018

BMC Cardiovasc Disord

325

305

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“…This "acute service "component of a HF unit, often involving outpatient intravenous therapies, is very effective at aborting the need for admission [31] and in our experience is required by approximately 30% of patients in the first three months post discharge [32].…”

Section: Deteriorating Patientmentioning

confidence: 83%

Developing a disease management program for the improvement of heart failure outcomes: the do’s and the don’ts

Healy

Ledwidge

Gallagher

et al. 2019

Expert Review of Cardiovascular Therapy

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“…Furthermore, patients with HFpEF have a significantly higher mean number of outpatient and emergency room visits compared with patients with HFrEF, although the absolute difference is low (1.4 and 0.3 annual visits, respectively) [30]. These differences may be driven by visits related to non-CV comorbidities [38,60]. In turn, this can translate into higher disease management costs for patients with HFpEF versus HFrEF, placing a significant financial burden on health-care systems [60].…”

Section: Impact On the Clinic And Resource Utilizationmentioning

confidence: 99%

Heart failure with preserved ejection fraction: disease burden for patients, caregivers, and the health-care system

Tóth

Gauthier

2020

Postgraduate Medicine

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Heart failure with preserved ejection fraction (HFpEF) will soon become the most prevalent form of HF because of an aging population and an accompanying increase in the number of risk factors for this disease. The high frequency of comorbidities typical of this population contributes to an increased risk for hospitalization and death. It is also partially responsible for the symptomatic deterioration that results in hospitalization and impaired quality of life and functional capacity in patients. The effects of HFpEF are felt by patients and their caregivers, who might experience detriment to their own health and their social and working lives. Financial burden is associated with HFpEF, stemming from hospitalization and long-term care costs, as well as absenteeism from work in the case of caregivers. Early identification of patients at risk and aggressive management are key to preventing this disease and its progression.

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A comparison of HFrEF vs HFpEF's clinical workload and cost in the first year following hospitalization and enrollment in a disease management program

Cited by 25 publications

References 18 publications

Cost-of-illness studies in heart failure: a systematic review 2004–2016

Cost-of-illness studies in heart failure: a systematic review 2004–2016

Developing a disease management program for the improvement of heart failure outcomes: the do’s and the don’ts

Heart failure with preserved ejection fraction: disease burden for patients, caregivers, and the health-care system

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