A comparison of four serological tests for the diagnosis of caseous lymphadenitis in sheep and goats

Dercksen, D.; Brinkhof, J.; Dekker-Nooren, Toos; Maanen, Kees van; Bode, Carel F; Baird, Graham; Kamp, E. M.

doi:10.1016/s0378-1135(00)00217-0

Cited by 63 publications

(71 citation statements)

References 10 publications

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“…ELISA is favored due to its high sensitivity and specificity as well as convenience (simplicity, possibility of automation and applicability to large number of samples) (Sutherland et al 1987, Ter Laak and Shreuder 1991, Menzies et al 1994, Sting et al 1998, Binns et al 2007). In case of CLA, ELISA is of much higher validity in goats than in sheep (Dercksen et al 2000). The ELISA used in the study had quite high sensitivity and specificity (Kaba et al 2001) when compared with four other ELISA evaluated by Dercksen et al (2000).…”

Section: Discussionmentioning

confidence: 86%

“…In case of CLA, ELISA is of much higher validity in goats than in sheep (Dercksen et al 2000). The ELISA used in the study had quite high sensitivity and specificity (Kaba et al 2001) when compared with four other ELISA evaluated by Dercksen et al (2000).…”

Section: Discussionmentioning

confidence: 86%

“…Several serological tests for detecting CLA are available (Brown et al 1986, Brown et al 1987, Menzies and Muckle 1989, Literak et al 1995, Dercksen et al 2000. ELISA is favored due to its high sensitivity and specificity as well as convenience (simplicity, possibility of automation and applicability to large number of samples) (Sutherland et al 1987, Ter Laak and Shreuder 1991, Menzies et al 1994, Sting et al 1998, Binns et al 2007).…”

Section: Discussionmentioning

confidence: 99%

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Evaluation of the risk factors influencing the spread of caseous lymphadenitis in goat herds

Kaba¹,

Nowicki²,

Frymus³

et al. 2011

Polish Journal of Veterinary Sciences

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Epidemiological studies on caseous lymphadenitis were carried out in Poland in 1996 and 2002 among goat herds covered by a milk recording program. Between-herd seroprevalence was 13.2% in 1996 and increased to 62.5% in 2002. The average size of seropositive herds was statistically significantly higher than that of seronegative ones, however there was no statistically significant difference in the age between the herds. A statistically significant prevalence ratio (PR) was identified and relevant attributable risk for exposed animals (AR exp ) was calculated for the following risk factors: presence of seropositive males in a herd (PR=8.350; AR exp =0.651), presence of superficial abscesses in animals (PR=6.142; AR exp =0.620), presence of respiratory signs (PR=2.900; AR exp =0.393), presence of animals in poor condition in a herd (PR=2.774; AR exp =0.390) and occurrence of reproductive failures in a herd (PR=1.798; AR exp =0.230). Purchase of animals from abroad, mastitis and husbandry conditions (housing system, grazing system, hygienic conditions) were not shown to be statistically significant risk factors.

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Section: Discussionmentioning

confidence: 86%

Section: Discussionmentioning

confidence: 86%

Section: Discussionmentioning

confidence: 99%

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Evaluation of the risk factors influencing the spread of caseous lymphadenitis in goat herds

Kaba¹,

Nowicki²,

Frymus³

et al. 2011

Polish Journal of Veterinary Sciences

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“…Diagnosis is based on characteristics of the pathological lesions (presence of external abscesses), and this confirmation diagnosis,isolation, and biochemical identification, mainly to differentiate other pathogens that also cause abscesses, such as Arcanobacterium pyrogens and Pasteurella multocida (Dercksen et al, 2000;Dorella et al, 2006). PCR diagnosis using specific primers for C. pseudotuberculosis, which is a significant role in the control of disease outbreaks in any regions (Çetinkaya et al, 2002).…”

Section: Advances In Animal and Veterinary Sciencesmentioning

confidence: 99%

Suppurative Pneumonia and Lymphadenitis in a Goat Associated with Infection by Corynebacterium Pseudotuberculosis A Case Study

Singh¹,

Kumari²,

Yadav³

et al. 2017

Adv. Anim. Vet. Sci.

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“…Nevertheless, some enzyme-linked immunosorbent assay (ELISA)-based diagnostic tests have been reported to be effective in control and eradication programs [32,33,110]. Recently, ELISA tests to detect gamma interferon (IFN-γ), as a marker of cell-mediated immunity against C. pseudotuberculosis, have been developed [71,86,93].…”

Section: Diagnosis and Control Of Clamentioning

confidence: 99%

Corynebacterium pseudotuberculosis: microbiology, biochemical properties, pathogenesis and molecular studies of virulence

et al. 2006

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-Corynebacterium pseudotuberculosis is the etiological agent of caseous lymphadenitis (CLA), a common disease in small ruminant populations throughout the world. Once established, this disease is difficult to eradicate because drug therapy is not effective and because the clinical detection of infected animals is of limited efficiency. We reviewed the microbiological, biochemical and taxonomic features of C. pseudotuberculosis, general aspects of infection, the main virulence determinants and currently available commercial vaccines. We also examined the current molecular strategies for the study of virulence in C. pseudotuberculosis, including the latest research on the identification of novel virulence factors and genes, which will help us to better understand the biology of this microorganism. This knowledge may also contribute to the development of improved CLA vaccines, including subunit and DNA-based types, as well as to improve the diagnosis, treatment and control of this disease.

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A comparison of four serological tests for the diagnosis of caseous lymphadenitis in sheep and goats

Cited by 63 publications

References 10 publications

Evaluation of the risk factors influencing the spread of caseous lymphadenitis in goat herds

Evaluation of the risk factors influencing the spread of caseous lymphadenitis in goat herds

Suppurative Pneumonia and Lymphadenitis in a Goat Associated with Infection by Corynebacterium Pseudotuberculosis A Case Study

Corynebacterium pseudotuberculosis: microbiology, biochemical properties, pathogenesis and molecular studies of virulence

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