A comparison of different diagnostic criteria of acute kidney injury in critically ill patients

Luo, Xu‐Ying; Jiang, Li; Du, Bin; Wen, Ying; Wang, Meiping; Xi, Xiuming

doi:10.1186/cc13977

Cited by 247 publications

(203 citation statements)

References 31 publications

(37 reference statements)

Supporting

Mentioning

172

Contrasting

Unclassified

Order By: Relevance

“…17 Similar findings were also reported in a study with 3100 critically ill patients. 5 KDIGO identified more patients with AKI than RIFLE (51% vs. 46.9%; p ¼ 0.001) or AKIN (51% vs. 38.4%; p < 0.001). Therefore, based on currently available evidence, KDIGO is at least as good as, and in some situations even better than the AKIN and RIFLE.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Septic acute kidney injury in critically ill patients – a single-center study on its incidence, clinical characteristics, and outcome predictors

et al. 2016

View full text Add to dashboard Cite

Purpose The objective of this study is to examine the incidence, clinical characteristics, and outcome (90-day mortality) of critically ill Chinese patients with septic AKI. Methods Patients admitted to the ICU of a regional hospital from 1 January 2011 to 31 December 2013 were included, excluding those on chronic renal replacement therapy. AKI was defined using KDIGO criteria. Patients were followed till 90 days from ICU admission or death, whichever occurred earlier. Demographics, diagnosis, clinical characteristics, and outcome were analyzed. Results In total, 3687 patients were included and 54.7% patients developed AKI. Sepsis was the most common cause of AKI (49.2%). Compared to those without AKI, AKI patients had higher disease severity, more physiological and biochemical disturbance, and carried significant co-morbidities. Ninety-day mortality increased with severity of AKI (16.7, 27.5, and 48.3% for KDIGO stage 1, 2, and 3 AKI, p < 0.001). Full renal recovery was achieved in 71.6% of AKI patients. Compared with non-septic AKI, septic AKI was associated with higher disease severity and required more aggressive support. Non-recovery of renal function occurred in 2.5% of patients with septic AKI, compared with 6.4% in non-septic AKI (p < 0.001). Cox regression analysis showed that age, emergency ICU admission, post-operative cases, admission diagnosis, etiology of AKI, disease severity score, mechanical ventilation, vasopressor support, and blood parameters (like albumin, potassium and pH) independently predicted 90-day mortality. Conclusions AKI, especially septic AKI is common in critically ill Chinese patients and is associated with poor patient outcome. Etiology of AKI has a significant impact on 90-day mortality and may affect renal outcome. ARTICLE HISTORY

show abstract

Section: Discussionmentioning

confidence: 99%

“…4 Study by Luo et al 5 showed that KDIGO identified more patients with AKI than RIFLE or AKIN classification system. The etiology of AKI is often multifactorial.…”

Section: Introductionmentioning

confidence: 99%

Septic acute kidney injury in critically ill patients – a single-center study on its incidence, clinical characteristics, and outcome predictors

et al. 2016

View full text Add to dashboard Cite

show abstract

“…Seven observational studies251, 252, 253, 254, 255, 256, 257 examining patient mortality rate as a clinical outcome were extracted during an assessment comparing the KDIGO guidelines and the AKIN and RIFLE criteria, and as a result of comparing AKI diagnoses based on the KDIGO guidelines with diagnoses based on the RIFLE or AKIN criteria, diagnoses based on the AKIN criteria were found to have higher accuracy or were reflective of similar in‐hospital mortality rates. Although only the study by Peng et al 257.…”

Section: Cq12: Acute Kidney Injury/blood Apheresismentioning

confidence: 99%

The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2016 (J‐SSCG2016)

Nishida

Ogura

Egi

et al. 2018

Acute Medicine & Surgery

157

View full text Add to dashboard Cite

Background and PurposeThe Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2016 (J‐SSCG 2016), a Japanese‐specific set of clinical practice guidelines for sepsis and septic shock created jointly by the Japanese Society of Intensive Care Medicine and the Japanese Association for Acute Medicine, was first released in February 2017 in Japanese. An English‐language version of these guidelines was created based on the contents of the original Japanese‐language version.MethodsMembers of the Japanese Society of Intensive Care Medicine and the Japanese Association for Acute Medicine were selected and organized into 19 committee members and 52 working group members. The guidelines were prepared in accordance with the Medical Information Network Distribution Service (Minds) creation procedures. The Academic Guidelines Promotion Team was organized to oversee and provide academic support to the respective activities allocated to each Guideline Creation Team. To improve quality assurance and workflow transparency, a mutual peer review system was established, and discussions within each team were open to the public. Public comments were collected once after the initial formulation of a clinical question (CQ), and twice during the review of the final draft. Recommendations were determined to have been adopted after obtaining support from a two‐thirds (>66.6%) majority vote of each of the 19 committee members.ResultsA total of 87 CQs were selected among 19 clinical areas, including pediatric topics and several other important areas not covered in the first edition of the Japanese guidelines (J‐SSCG 2012). The approval rate obtained through committee voting, in addition to ratings of the strengths of the recommendation and its supporting evidence were also added to each recommendation statement. We conducted meta‐analyses for 29 CQs. Thirty seven CQs contained recommendations in the form of an expert consensus due to insufficient evidence. No recommendations were provided for 5 CQs.ConclusionsBased on the evidence gathered, we were able to formulate Japanese‐specific clinical practice guidelines that are tailored to the Japanese context in a highly transparent manner. These guidelines can easily be used not only by specialists, but also by non‐specialists, general clinicians, nurses, pharmacists, clinical engineers, and other healthcare professionals.

show abstract

“…31 Based on the maximum value of available postoperative creatinine, patients were categorized in mutually exclusive categories of creatinine change and corresponding stages of AKI according to the KDIGO definition, 27 including no follow-up (no F/U), no measured increase (ΔCr ≤ 0%), slight increase (ΔCr 1 to 24%), minor increase (ΔCr 25 to 49%), KDIGO stage 1 (ΔCr 50 to 99%, corresponding to RIFLE R or AKIN 1), KDIGO stage 2 (ΔCr 100 to 199%, RIFLE I or AKIN 2), and KDIGO stage 3 (ΔCr ≥ 200%, RIFLE F or AKIN 3). 27,29,30 According to KDIGO guidelines, patients were categorized to the highest category possible.…”

Section: Definition Of Aki and Aki Severitymentioning

confidence: 99%

Minor Postoperative Increases of Creatinine Are Associated With Higher Mortality and Longer Hospital Length of Stay in Surgical Patients

Kork

Balzer

Spies

et al. 2016

Survey of Anesthesiology

View full text Add to dashboard Cite

show abstract

A comparison of different diagnostic criteria of acute kidney injury in critically ill patients

Cited by 247 publications

References 31 publications

Septic acute kidney injury in critically ill patients – a single-center study on its incidence, clinical characteristics, and outcome predictors

Septic acute kidney injury in critically ill patients – a single-center study on its incidence, clinical characteristics, and outcome predictors

The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2016 (J‐SSCG2016)

Minor Postoperative Increases of Creatinine Are Associated With Higher Mortality and Longer Hospital Length of Stay in Surgical Patients

Contact Info

Product

Resources

About