A comparison of desflurane and sevoflurane in the recovery of cognitive function after general anesthesia in elderly patients

Jadhav, Pandurang Kondiba

doi:10.18203/2320-6012.ijrms20151176

Cited by 4 publications

(4 citation statements)

References 17 publications

(14 reference statements)

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“…found early recovery of cognitive function with sevoflurane when compared with desflurane. [ 5 ] They also used different tools to assess the recovery of cognitive function, which was not standardised. [ 1 6 15 16 ]…”

Section: Discussionmentioning

confidence: 99%

“…[ 4 ] The faster recovery after desflurane and sevoflurane anaesthesia compared with other inhaled anaesthetics is attributable to their low solubility (blood-gas partition coefficient are 0.69 and 0.42, respectively). [ 5 ] Though the difference between the blood-gas coefficient seems minimal, it has been observed that there is a significant difference in the recovery profile of these two inhaled anaesthetics. Recent studies suggest that desflurane compared to sevoflurane leads to earlier recovery of airway reflexes.…”

Section: Introductionmentioning

confidence: 99%

“…[ 2 3 ] However, comparative results of recovery of cognitive function vary significantly. [ 5 6 ] After standardising all the factors that can affect recovery from anaesthesia, this study was conducted with the aim of evaluating and comparing the times of recovery of airway reflexes and cognitive function following sevoflurane and desflurane anaesthesia.…”

Section: Introductionmentioning

confidence: 99%

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Comparative study of recovery of airway reflexes and cognitive function following sevoflurane versus desflurane anaesthesia

2021

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Background and Aims: Sevoflurane and desflurane have almost similar blood-gas solubility but recent studies suggest that desflurane compared to sevoflurane leads to faster recovery of airway reflexes, but the recovery of cognitive function varies significantly. We conducted this study to compare the times of recovery from anaesthesia following desflurane versus sevoflurane anaesthesia. Methods: This randomised double-blinded study was conducted on 60 patients of American Society of Anesthesiologists (ASA) classification I–II, age between 18 and 60 years with body mass index (BMI) ≤30 kg/m 2 who underwent elective cholecystectomy. A standard general anaesthesia protocol was followed with either sevoflurane (group A = 30 patients) or desflurane (group B = 30 patients) along with bispectral index and neuromuscular monitoring. Following extubation, tests for recovery of airway reflexes and cognitive function were conducted and various time intervals were noted. Statistical analysis was carried out using Statistical Package for Social Sciences (SPSS) standard software version 17. Results: The mean time from first verbal response to first passing the swallowing test was comparable in both the groups (5.50 ± 3.45 vs. 4.10 ± 3.42 min, P value = 0.120). Patients receiving desflurane showed faster response to verbal commands (5.93 ± 4.13 vs. 8.20 ± 3.39 min, P value = 0.024), passed the swallowing test earlier (10.03 ± 4.97 vs. 13.70 ± 3.48 min, P value = 0.009) and Short orientation memory concentration test (SOMCT) earlier (9.83 ± 4.51 vs. 14.10 ± 4.31 min, P value ≤0.001) compared to sevoflurane. Conclusion: In patients undergoing laparoscopic cholecystectomy under controlled conditions, earlier recovery is seen with desflurane compared to sevoflurane.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Comparative study of recovery of airway reflexes and cognitive function following sevoflurane versus desflurane anaesthesia

2021

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“…It has been reported that the patients suffering from OCD can be severely impaired in their ability to read and maintain attention, which suggests that there are serious defects in the cognitive function of the patients with OCD [5]. The sudden, unpredictable traumas that are severely destructive with major casualties not only can cause serious psychological stress to the family members and relatives of the trauma patients, but also can bring about negative impacts [6,7]. For example, the occurrence of sudden and devastating trauma, the huge property loss and casualties thus caused, the terrible and difficult scenes that the survivors have experienced, the possible injury, the possible loss of loved ones and the further possible psychological trauma thus suffered [8].…”

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confidence: 99%

Effect of the Combination of Biofeedback and Sequential Psychotherapy on the Cognitive Function of Trauma Patients Based on the Fusion of Set Theory Model

ZHANG¹,

Yuan²

2020

pharmaceutical-sciences

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Zhang and Yuan: Effect of the Combination of Biofeedback and Sequential Psychotherapy on the Cognitive Function of Trauma Patients Based on the Fusion of Set Theory Model This study intended to take a special group of trauma patients as research subjects to propose a method analysing the effect of combination of biofeedback and sequential psychotherapy based on the fusion of the set theory model on the cognitive function of these patients with trauma. The occurrence and development of post-traumatic stress disorder and the cognitive function is investigated. The set theory model is used in this study to carry out a survey on the effect of the combination of biofeedback and sequential psychotherapy on patients with post-traumatic stress disorder to describe the occurrence, development, change trajectory and time course characteristics of post-traumatic stress disorder. The set theory model was employed to investigate the cognitive development characteristics of these trauma patients. In addition, through the set theory model, psychological behavior mechanism for the occurrence and development of post-traumatic stress disorder is revealed. The study of the combination of biofeedback and sequential psychotherapy is adopted to investigate the effect of the post-traumatic stress disorder on the cognitive function of the trauma patients. The results of this study could be used to provide scientific advice for the placement and psychological assistance of trauma patients in future, to provide a scientific basis for a targeted psychological intervention and overall planning of the intervention, and to provide scientific and objective indicators and methods for the diagnosis and assessment of intervention of traumatic psychology in patients with trauma in the future.

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Inhalational Anesthetics

Haynes¹

2017

Geriatric Anesthesiology

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A comparison of desflurane and sevoflurane in the recovery of cognitive function after general anesthesia in elderly patients

Cited by 4 publications

References 17 publications

Comparative study of recovery of airway reflexes and cognitive function following sevoflurane versus desflurane anaesthesia

Comparative study of recovery of airway reflexes and cognitive function following sevoflurane versus desflurane anaesthesia

Effect of the Combination of Biofeedback and Sequential Psychotherapy on the Cognitive Function of Trauma Patients Based on the Fusion of Set Theory Model

Inhalational Anesthetics

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