BackgroundPreoperative anxiety, and to some extent depression, predict the perceived impact of somatic symptoms (such as dumping, pain, and fatigue) one year after Roux-en-Y gastric bypass (RYGB). Negative attention to and interpretation of somatic symptoms may thus be associated with post-operative changes in affect.
ObjectivesThe aim of this study was to explore whether preoperative anxiety and depressive symptoms predicted the perceived impact of somatic symptoms three years after RYGB.Secondly, we aimed to examine the three-year trajectory of depressive and anxiety symptoms, and their interaction with perceived somatic symptoms postoperatively.
SettingUniversity hospital.
MethodsPre-surgery, 1-, and 3-years post-surgery data were collected from 169 participants (62.4% follow-up). A cross-lagged, autoregressive regression analysis was employed to examine the mutual interaction of trajectories over the follow-up period.
ResultsFatigue (30.8%) and dumping (23.7%) were common high-impact symptoms three years postoperatively. Pre-surgery anxiety was associated with higher impact of fatigue (p<.001), pain (p<.001), and diarrhea (p<.001), while pre-surgery depressive mood was related to reporting higher impact of diarrhea (p<.01) at 3-year follow-up. Higher anxiety/depression symptoms were related to higher perceived total symptom impact at one and three years postoperatively, controlling for percent total weight loss. Higher impact of somatic symptoms at one-year post-surgery predicted a significant increase in depressive symptoms 3-years postsurgery.
ConclusionHigher perceived total symptom burden (pain, fatigue, dumping, diarrhea, and vomiting) at one-year post-surgery predicted increase in depression over the next two years. The results underscore the importance of managing somatic symptoms after surgery to prevent patients' distress..