A Comparison of 0.5% Bupivacaine and 0.5% Ropivacaine for Brachial Plexus Block

Hickey, Rosemary; Blanchard, Janna; Hoffman, Joan; Ramamurthy, Somayaji

doi:10.1213/00000539-199002001-00156

Cited by 33 publications

(50 citation statements)

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“…Ropivacaine has slightly shorter duration of sensory and motor block as compared to bupivacaine. Hickey et al [14] reported same observations. Also, ropivacaine has shorter duration of analgesia than bupivacaine.…”

Section: Discussionsupporting

confidence: 52%

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Comparative Study of Ropivacaine 0.5% with fentanyl and Bupivacaine 0.5% with fentanyl in Interscalene Brachial Plexus Block

Barsagade¹,

Tarkase²,

Gate³

2016

Int J of Biomed & Adv Res

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Aim and Objective: Aim of the present study was to compare the clinical characteristics of ropivacaine 0.5% and bupivacaine 0.5% with fentanyl when used for interscalene brachial plexus block. Methodology: In this prospective randomized double blind study, 60 patients were randomly divided into two groups, group BF-bopivacaine with fentanyl and group RF-ropivacaine with fentanyl. Effects in terms of onset, duration and quality of sensory and motor blockade, pulse and blood pressure, respiration were monitored and complications of interscalene brachial plexus block were also noted. Results: The mean onset time of sensory and motor blockade was 2.65 and 4.31 minutes in group BF and 4.08 and 6.08 minutes in group RF group respectively. The mean duration of sensory and motor block was 644.44 min and 595.55 min in group BF respectively. Whereas, in group RF the mean duration of sensory and motor block was 573.46 min and 513.46 min respectively. Mean VAS preoperatively was comparable among two groups perioperatively and till 7 hr after block placement (p> 0.05) all patient depicted a VAS score 0 up to 6 hr. The requirement of rescue analgesic was earlier with ropivacaine as compared to bupivacaine. Conclusion: Ropivacaine has the margin of safety than bupivacaine. Ropivacaine with an almost comparable blockade profile would be the better choice in view of safety of the patient.

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Section: Discussionsupporting

confidence: 52%

“…Ropivacaine and bupivacaine produced almost similar quality of sensory and motor block but quality of the block was little better with bupivacaine. Klien et al [2] and Hickey et al [14] and Eroglu et al [15] also reported the same findings. Ropivacaine has slightly shorter duration of sensory and motor block as compared to bupivacaine.…”

Section: Discussionmentioning

confidence: 54%

Comparative Study of Ropivacaine 0.5% with fentanyl and Bupivacaine 0.5% with fentanyl in Interscalene Brachial Plexus Block

Barsagade¹,

Tarkase²,

Gate³

2016

Int J of Biomed & Adv Res

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“…These frequencies with ropivacaine 7.5 mg.m1-1 are, however, less than those obtained with 32 ml ropivacaine mg.m1-1 as reported by Hickey et al s The frequency of motor block was also lower than the 83-91% reported by Hickey et al s Possible reasons for a lower efficacy in this study are: variations in technical proficiency among a much larger group of anesthesiologists (12 vs 2), fewer patients blocked per anesthesiologist, differences in nerve localisation techniques between anesthesiologists, a slightly lower volume used in the present study (30 vs 32 ml), and a slightly different method of recording successful analgesia and anesthesia (nerves vs dermatomes). In the study by Hickey et al 3 needle localization was exclusively determined by eliciting paresthesia. In spite of this it is important to note that the majority of patients had successful anesthesia in the relevant dermatomes to allow surgery to proceed without resort to general anesthesia.…”

Section: Discussionmentioning

confidence: 99%

“…It exhibits less CNS and cardio-toxicity 1-2 than bupivacaine and is effective when used for brachial plexus anesthesia, s-4 Brachial plexus block with a solution of ropivacaine 2.5 mg.m1-1 frequently required supplementation 4 while ropivacaine 5.0 mg.ml -I was comparable to bupivacaine 5.0 mg-mlq. 3 We hypothesized that a further increase in the ropivacaine dose would result in increased efficacy and duration for brachial plexus anesthesia.…”

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confidence: 99%

A multicentre trial of ropivacaine 7.5 mg·ml−1 vs bupivacaine 5 mg·ml−1 for supra clavicular brachial plexus anesthesia

Vaghadia

Chan

Ganapathy

et al. 1999

Can J Anesth/J Can Anesth

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Purpose: To compare the efficacy of ropivacaine 7.5 mgml -~ with bupivacaine 5.0 mg'ml -~ for subclavian perivascular brachial plexus block. Methods: After informed consent, 104 ASA I-III adults participated in a randomized, double-blind, multi-center trial to receive 30 ml of either ropivacaine 7.5 mg'ml -~ or bupivacaine 5.0 mg.ml -I for subclavian perivascular brachial plexus block prior to upper limb surgery. Onset and duration of sensory and motor block in the distribution of the axillary, median, musculo-cutaneous, radial and ulnar nerves were assessed. Results: Onset times and duration of sensory and motor block were similar between groups. Mean duration of analgesia for the five nerves was between I 1.3 and 14.3 hr with ropivacaine and between 10.3 and 17. I hr with bupivacaine. Quality of muscle relaxation judged as excellent by the investigators was not significantly different (ropivacaine -35/49, bupivacaine -30/49). The median time to first request for analgesia was comparable between the two groups (I I-12 hr). One patient developed a grand mal seizure shortly after receiving bupivacaine and recovered consciousness within 30 min. There were no serious adverse events in the ropivacaine group. Conclusions: Thirty ml ropivacaine 7.5 mg.ml -~ (225 mg) produced effective and well tolerated brachial plexus block of long duration by the subclavian perivascular route. In this study, the results were similar to those of 30 ml bupivacaine 5.0 mg-ml -I.Objec'df: Comparer I'efficacit6 de 7,5 mg-ml -~ de ropivaca~fne avec 5,0 mg'ml-~de bupivacai'ne dans le cas d'un blocage p&ivasculaire sous-clavier du plexus brachial. M&hode : Ayant ~t6 bien inform&, 104 adultes ASA 1411 ont consenti/~ participer ~ un essai multicentrique, randomis6 et en double aveugle et ont regu 30 ml de ropivaca'ine 7,5 mg'ml -~ ou de bupivacai'ne 5,0 mg'ml -I pour un blocage p&ivasculaire sous-clavier du plexus brachial, pr&6dant une intervention au membre sup&ieur. On a not~ le d6but et la dur~e du blocage sensitif et moteur selon la distribution des nerfs axillaire, m6dian, muscuIo-cutan6, radial et cubital. REsultats : Le d6but et la dur6e du blocage sensitif et moteur ont 6t6 similaires dans les deux groupes. La dur& moyenne de I'analg&ie pour les cinq nerfs se situait entre I 1,3 et 14,3 h avec la ropivaca'ine et entre 10,3 et 17, I h avec la bupivacai"ne. La qualit~ du rel~chement musculaire, jugEe excellente par les chercheurs, n'a pas pr&en-t6 de diff&ence intergroupe significative (ropivaca'ine -35/49, bupivacai"ne -30/49). Le temps moyen &oul6 jusqu'~ la premi&e demande d'analg&ique a &6 comparable 6galement (I I -12 h). Un patient a subi une crise d'6pilepsie peu apr& avoir regu la bupivaca'ine et est redevenu conscient en moins de 30 min. II n'y a pas eu d'incident d~favorable important dons le groupe ropivaca~ine. Conclusion : Trente millilitres de ropivaca'ine 7,5 mg-ml -t (225 mg) ont produit un blocage du plexus brachial effcace, de Iongue dur& et bien to16r6, par voie p&ivasculaire sous-clavi&e. Les r6sultats ont 6t6 simil...

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“…These cocktails have been shown to be effective in the acute perioperative period but have finite periods of action. Traditional amide local anesthetics such as bupivacaine or ropivacaine (which is reported to have a faster onset than bupivacaine but with a similar duration of action [2,7,11,12,22,25,37,41,50,52,55,58,74,86]) have been the mainstay of most TKA PAI cocktails. In addition to amide local anesthetics, some investigators have chosen to also include intrathecal morphine as part of their pain management protocol.…”

Section: Introductionmentioning

confidence: 99%

No Difference in Early Analgesia Between Liposomal Bupivacaine Injection and Intrathecal Morphine After TKA

Barrington

Emerson

Lovald

et al. 2017

Clinical Orthopaedics &Amp; Related Research

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Background Opioid analgesics have been a standard modality for postoperative pain management after total knee arthroplasty (TKA) but are also associated with increased risk of nausea, pruritus, vomiting, respiratory depression, prolonged ileus, and cognitive dysfunction.There is still a need for a method of anesthesia that can deliver effective long-term postoperative pain relief without incurring the high cost and health burden of opioids and nerve blocks. Questions/purposes (1) Is liposomal bupivacaine-based periarticular injection (PAI) more effective than morphinebased spinal anesthesia or ropivacaine-based PAI in

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A Comparison of 0.5% Bupivacaine and 0.5% Ropivacaine for Brachial Plexus Block

Cited by 33 publications

References 0 publications

Comparative Study of Ropivacaine 0.5% with fentanyl and Bupivacaine 0.5% with fentanyl in Interscalene Brachial Plexus Block

Comparative Study of Ropivacaine 0.5% with fentanyl and Bupivacaine 0.5% with fentanyl in Interscalene Brachial Plexus Block

A multicentre trial of ropivacaine 7.5 mg·ml−1 vs bupivacaine 5 mg·ml−1 for supra clavicular brachial plexus anesthesia

No Difference in Early Analgesia Between Liposomal Bupivacaine Injection and Intrathecal Morphine After TKA

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