A Comparison Between Unidirectional Current Nonconvulsive Electrical Stimulation Given With Reiter's Machine, Standard Alternating Current Electroshock (Cerletti Method), and Pentothal in Chronic Schizophrenia

Miller, Derek; Clancy, Jennifer A.; Cumming, Elaine

doi:10.1176/ajp.109.8.617

Cited by 67 publications

(38 citation statements)

References 4 publications

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“…4,8 We also note that no significant difference in short-term outcome was observed between ECT, sham ECT and nonconvulsive stimulation in catatonia associated with chronic schizophrenia. 12,13 …”

Section: Discussionmentioning

confidence: 99%

Catatonia in Psychotic Patients: Clinical Features and Treatment Response

England¹,

Ongur²,

Konopaske³

et al. 2011

Journal of Neuropsychiatry

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Section: Discussionmentioning

confidence: 99%

Catatonia in Psychotic Patients: Clinical Features and Treatment Response

England¹,

Ongur²,

Konopaske³

et al. 2011

Journal of Neuropsychiatry

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“…All but one of the early studies (e.g. Miller et al, 1953;Brill et al, 1959) found no significant differences between ECT and SECT. The exception did find short-term differences on psychotic symptoms but not on readiness for discharge (Ulett et al, 1956).…”

Section: Effectiveness During Treatment Periodmentioning

confidence: 93%

The effectiveness of electroconvulsive therapy: A literature review

Read

Bentall²

2010

Epidemiol Psychiatr Sci

105

113

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SUMMARYAim – To review the literature on the efficacy of electroconvulsive therapy [ECT], with a particular focus on depression, its primary target group. Methods – PsycINFO, Medline, previous reviews and meta-analyses were searched in an attempt to identify all studies comparing ECT with simulated-ECT [SECT]. Results – These placebo controlled studies show minimal support for effectiveness with either depression or ‘schizophrenia’ during the course of treatment (i.e. only for some patients, on some measures, sometimes perceived only by psychiatrists but not by other raters), and no evidence, for either diagnostic group, of any benefits beyond the treatment period. There are no placebo-controlled studies evaluating the hypothesis that ECT prevents suicide, and no robust evidence from other kinds of studies to support the hypothesis. Conclusions – Given the strong evidence (summarised here) of persistent and, for some, permanent brain dysfunction, primarily evidenced in the form of retrograde and anterograde amnesia, and the evidence of a slight but significant increased risk of death, the cost-benefit analysis for ECT is so poor that its use cannot be scientifically justified.Declaration of Interest: Neither author has any financial conflicts of interest in relation to this paper.

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“…All studies in the pre-antipsychotic era suffered problems in research methodology. Many reports were uncontrolled, used uncertain diagnostic criteria, and poorly characterized patient samples and outcome criteria [38][39][40][41][42][43]. In these early studies, outcomes after ECT were impressive for patients with relatively recent onset of illness, and recovery or marked improvement was documented in up to 75% of subjects [33]; however, ECT was considerably less effective in patients with insidious onset and long duration of illness [40,41,[44][45][46][47][48].…”

Section: Previous Studies On the Efficacy Of Ectmentioning

confidence: 99%

“…Among the early studies, only one found a therapeutic advantage for ECT [49], the others did not [43,[50][51][52][53]. Three sham ECT-controlled studies in the 1980s suggested short-lived clinical benefits [54][55][56], but these studies were also methodological flawed.…”

Section: Previous Studies On the Efficacy Of Ectmentioning

confidence: 99%

Electroconvulsive Therapy for Schizophrenia

Chanpattana¹

2007

CPSR

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The role of electroconvulsive therapy (ECT) in treating patients with schizophrenia remains unclear. This paper aims to determine whether ECT results in clinically meaningful benefit with regard to psychopathology, behavior and functioning for patients with schizophrenia, and whether variations in the practical administration of ECT influences outcome. Existing research in the field and the new information of research in patients with treatment-resistant schizophrenia (TRS) from Thailand are summarized. Independent of gender, duration of the current episode and severity of baseline negative symptoms predict outcome. Treatment results in marked improvement in positive symptoms, with an intermediate effect on affective symptoms, and no effect or worsening of negative symptoms. The combination of ECT and conventional antipsychotic drug is associated with better outcome than either ECT alone or antipsychotic drug alone during both acute and maintenance phases of treatment. This improvement is not only in psychopathology but also in quality of life and social functioning. Electrical stimulus doses 2-4 times the seizure threshold are likely to increase the speed of recovery with bilateral ECT. Thrice-weekly ECT elicits response faster than does twice-weekly ECT. Although this preliminary evidence supports the use of ECT in patients with TRS, the research base for its use is still inadequate and deserves better investigation.

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A Comparison Between Unidirectional Current Nonconvulsive Electrical Stimulation Given With Reiter's Machine, Standard Alternating Current Electroshock (Cerletti Method), and Pentothal in Chronic Schizophrenia

Cited by 67 publications

References 4 publications

Catatonia in Psychotic Patients: Clinical Features and Treatment Response

Catatonia in Psychotic Patients: Clinical Features and Treatment Response

The effectiveness of electroconvulsive therapy: A literature review

Electroconvulsive Therapy for Schizophrenia

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